1. Tettelin,H., Masignani,V., Cieslewicz,M.J., et al. "Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae" Proc. Natl. Acad. Sci. U.S.A. 99 (19), 12391-12396 (2002) PMID 12200547 GenBank accession NC_004116 (under the aegis of TIGR).
2. Glaser,P., Rusniok,C., Chevalier,F., et al. "Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease" Mol. Microbiol. 45 (6), 1499-1513 (2002) PMID 12354221 GenBank accession NC_004368 (under the aegis of the Institute Pasteur).
The Tettelin and colleagues' source was a serotype V organism denoted 2603 V/R; it was this genomic sequence that became the basis for this database, although the annotation herein is independent. Strain 2603 is declared by the TIGR team to be 2.16 Mb and encode 2175 genes. The Glaser et al. source was a serotype III organism denoted NEM316. Those authors report a genome size of 2.21 Mb with 2118 genes.
At least two plasmids have been studied and sequenced in relation to S. agalactiae, pGB354 (Acc. NC_001797) and pGB3631 (Acc. NC_002136). Also, we have identified more than 100 references from the molecular subset of Medline covering year 2000 to the present that pertain to S. agalactiae (S. agalactiae references).
The core information in this database is the table of annotated records, one for each of LANL's 2124 predicted open reading frames. Each gene record is identified by a gene id, SAG0001-SAG2175. Record designations have some discontinuities since the total number of records is fewer than the final record number. Basic summaries of specific information are available below in the Predefined Database Searches that contain links to the particular gene record. Specialized analysis sections of the database are available below in the Specialized Analysis section and include a proteome comparison of S. agalactiae, S. pyogenes, S. mutans and S. pneumoniae.
Browsing and searching are also facilitated by the 'Functional Classes', 'EC Table', and 'Biochemical Pathways' summaries. For precise inquiries on the other hand, start with the search capabilities and their associated tables. We invite anyone with questions or suggestions to contact us at firstname.lastname@example.org.
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