Pseudorabies virus



2003 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Aleman N, Quiroga MI, Lopez-Pena M, Vazquez S, Guerrero FH, Nieto JM.
L-particle production during primary replication of pseudorabies virus in the nasal mucosa of swine.
J Virol. 2003 May;77(10):5657-67.
PMID: 12719558

Kerman IA, Enquist LW, Watson SJ, Yates BJ.
Brainstem substrates of sympatho-motor circuitry identified using trans-synaptic tracing with pseudorabies virus recombinants.
J Neurosci. 2003 Jun 1;23(11):4657-66.
PMID: 12805305

Krout KE, Mettenleiter TC, Loewy AD.
Single cns neurons link both central motor and cardiosympathetic systems: a double-virus tracing study.
Neuroscience. 2003;118(3):853-66.
PMID: 12710992

Kopp M, Granzow H, Fuchs W, Klupp BG, Mundt E, Karger A, Mettenleiter TC.
The pseudorabies virus UL11 protein is a virion component involved in secondary envelopment in the cytoplasm.
J Virol. 2003 May;77(9):5339-51.
PMID: 12692236

Taharaguchi S, Kon Y, Yoshino S, Ono E.
Impaired development of the cerebellum in transgenic mice expressing the immediate-early protein IE180 of pseudorabies virus.
Virology. 2003 Mar 15;307(2):243-54.
PMID: 12667794

2002 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Boldogkoi Z, Szabo A, Vrbova G, Nogradi A.
Pseudorabies virus-based gene delivery to rat embryonic spinal cord grafts.
Hum Gene Ther. 2002 Apr 10;13(6):719-29.
PMID: 11936971

Chang YY, Wong ML, Lin HW, Chang TJ.
Cloning and regulation of the promoter of pseudorabies virus (TNLstrain) glycoprotein E gene.
Virus Genes. 2002 Jun;24(3):235-41.
PMID: 12086144

del Rio T, Werner HC, Enquist LW.
The pseudorabies virus VP22 homologue (UL49) is dispensable for virus growth in vitro and has no effect on virulence and neuronal spread in rodents.
J Virol. 2002 Jan;76(2):774-82.
PMID: 11752167

Enquist LW, Tomishima MJ, Gross S, Smith GA.
Directional spread of an alpha-herpesvirus in the nervous system.
Vet Microbiol. 2002 Apr 22;86(1-2):5-16.
PMID: 11888685

Enquist LW.
Exploiting circuit-specific spread of pseudorabies virus in the central nervous system: insights to pathogenesis and circuit tracers.
J Infect Dis. 2002 Dec 1;186 Suppl 2:S209-14.
PMID: 12424699

Favoreel HW, Van Minnebruggen G, Nauwynck HJ, Enquist LW, Pensaert MB.
A tyrosine-based motif in the cytoplasmic tail of pseudorabies virus glycoprotein B is important for both antibody-induced internalization of viral glycoproteins and efficient cell-to-cell spread.
J Virol. 2002 Jul;76(13):6845-51.
PMID: 12050399

Fuchs W, Klupp BG, Granzow H, Osterrieder N, Mettenleiter TC.
The interacting UL31 and UL34 gene products of pseudorabies virus are involved in egress from the host-cell nucleus and represent components of primary enveloped but not mature virions.
J Virol. 2002 Jan;76(1):364-78.
PMID: 11739701

Fuchs W, Granzow H, Klupp BG, Kopp M, Mettenleiter TC.
The UL48 tegument protein of pseudorabies virus is critical for intracytoplasmic assembly of infectious virions.
J Virol. 2002 Jul;76(13):6729-42.
PMID: 12050386

Fuchs W, Klupp BG, Granzow H, Hengartner C, Brack A, Mundt A, Enquist LW,Mettenleiter TC.
Physical interaction between envelope glycoproteins E and M of pseudorabies virus and the major tegument protein UL49.
J Virol. 2002 Aug;76(16):8208-17.
PMID: 12134026

Hsiang CY.
Pseudorabies virus DNA-binding protein stimulates the exonuclease activity and regulates the processivity of pseudorabies virus DNase.
Biochem Biophys Res Commun. 2002 May 17;293(4):1301-8.
PMID: 12054518

Klupp BG, Fuchs W, Granzow H, Nixdorf R, Mettenleiter TC.
Pseudorabies virus UL36 tegument protein physically interacts with the UL37 protein.
J Virol. 2002 Mar;76(6):3065-71.
PMID: 11861875

Maeda K, Hayashi S, Tanioka Y, Matsumoto Y, Otsuka H.
Pseudorabies virus (PRV) is protected from complement attack by cellular factors and glycoprotein C (gC).
Virus Res. 2002 Mar 20;84(1-2):79-87.
PMID: 11900841

Prieto J, Solera J, Tabares E.
Development of new expression vector based on Pseudorabies virus amplicons: application to human insulin expression.
Virus Res. 2002 Oct;89(1):123-9.
PMID: 12367755

Struyf F, Martinez WM, Spear PG.
Mutations in the N-terminal domains of nectin-1 and nectin-2 reveal differences in requirements for entry of various alphaherpesviruses and for nectin-nectin interactions.
J Virol. 2002 Dec;76(24):12940-50.
PMID: 12438620

Taharaguchi S, Kobayashi T, Yoshino S, Ono E.
Analysis of regulatory functions for the region located upstream from the latency-associated transcript (LAT) promoter of pseudorabies virus in cultured cells.
Vet Microbiol. 2002 Mar 22;85(3):197-208.
PMID: 11852187

Taharaguchi S, Kobayashi T, Yoshino S, Ono E.
A pan-specific promoter activity of the 213bp segment of the pseudorabies virus early protein 0 gene in transgenicmice.
Arch Virol. 2002;147(1):11-9.
PMID: 11855625

Tomishima MJ, Enquist LW.
In vivo egress of an alphaherpesvirus from axons.
J Virol. 2002 Aug;76(16):8310-7.
PMID: 12134036

Yoon M, Spear PG.
Disruption of adherens junctions liberates nectin-1 to serve as receptor for herpes simplex virus and pseudorabiesvirus entry.
J Virol. 2002 Jul;76(14):7203-8.
PMID: 12072519

Zeenathul NA, Mohd-Azmi ML, Ali AS, Aini I, Sheik-Omar AR, Abdul-Rahim AM,Bahaman AR, Kamarudin AI.
Genomic variations among wildtype and mutant strains of pseudorabies virus.
Rev Argent Microbiol. 2002 Jan-Mar;34(1):7-14.
PMID: 11942085

2001 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Demmin GL, Clase AC, Randall JA, Enquist LW, Banfield BW.
Insertions in the gG gene of pseudorabies virus reduce expression of the upstream Us3 protein and inhibit cell-to-cell spread of virus infection.
J Virol. 2001 Nov;75(22):10856-69.
PMID: 11602726

Flamand A, Bennardo T, Babic N, Klupp BG, Mettenleiter TC.
The absence of glycoprotein gL, but not gC or gK, severely impairs pseudorabies virus neuroinvasiveness.
J Virol. 2001 Nov;75(22):11137-45.
PMID: 11602753

Granzow H, Klupp BG, Fuchs W, Veits J, Osterrieder N, Mettenleiter TC.
Egress of alphaherpesviruses: comparative ultrastructural study.
J Virol. 2001 Apr;75(8):3675-84.
PMID: 11264357

Klupp BG, Granzow H, Mundt E, Mettenleiter TC.
Pseudorabies virus UL37 gene product is involved in secondary envelopment.
J Virol. 2001 Oct;75(19):8927-36.
PMID: 11533156

Klupp BG, Granzow H, Mettenleiter TC.
Effect of the pseudorabies virus US3 protein on nuclear membrane localization of the UL34 protein and virus egress from the nucleus.
J Gen Virol. 2001 Oct;82(Pt 10):2363-71.
PMID: 11562530

Moore RJ, Vinsant S, McCauley AK, Kurukulasuriya NC, Godwin DW.
Transneuronal retrograde transport of attenuated pseudorabies viruses within central visual pathways.
Vis Neurosci. 2001 Jul-Aug;18(4):633-40.
PMID: 11829309

Nixdorf R, Klupp BG, Mettenleiter TC.
Role of the cytoplasmic tails of pseudorabies virus glycoproteins B, E and M in intracellular localization and virion incorporation.
J Gen Virol. 2001 Jan;82(Pt 1):215-26.
PMID: 11125174

Schmidt J, Gerdts V, Beyer J, Klupp BG, Mettenleiter TC.
Glycoprotein D-independent infectivity of pseudorabies virus results in an alteration of in vivo host range and correlates with mutations in glycoproteins B and H.
J Virol. 2001 Nov;75(21):10054-64.
PMID: 11581374

Shiau AL, Chu CY, Su WC, Wu CL.
Vaccination with the glycoprotein D gene of pseudorabies virus delivered by nonpathogenic Escherichia coli elicits protective immune responses.
Vaccine. 2001 Apr 30;19(23-24):3277-84.
PMID: 1131202

Tasaki T, Taharaguchi S, Kobayashi T, Yoshino S, Ono E.
Inhibition of pseudorabies virus replication by a dominant-negative mutant of early protein 0 expressed in a tetracycline-regulated system.
Vet Microbiol. 2001 Feb 12;78(3):195-203.
PMID: 11165064

Wagenaar F, Pol JM, de Wind N, Kimman TG.
Deletion of the UL21 gene in Pseudorabies virus results in the formation of DNA-deprived capsids: an electron microscopy study.
Vet Res. 2001 Jan-Feb;32(1):47-54.
PMID: 11254176

2000 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Ambagala AP, Hinkley S, Srikumaran S.
An early pseudorabies virus protein down-regulates porcine MHC class I expression by inhibition of transporter associated with antigen processing (TAP).
J Immunol. 2000 Jan 1;164(1):93-9.
PMID: 10604998

Aston-Jones G, Card JP.
Use of pseudorabies virus to delineate multisynaptic circuits in brain:opportunities and limitations.
J Neurosci Methods. 2000 Nov 15;103(1):51-61.
PMID: 11074095

Brideau AD, Card JP, Enquist LW.
Role of pseudorabies virus Us9, a type II membrane protein, in infection of tissue culture cells and the rat nervoussystem.
J Virol. 2000 Jan;74(2):834-45.
PMID: 10623746

Boldogkoi Z, Erdelyi F, Fodor I.
A putative latency promoter/enhancer (P(LAT2)) region of pseudorabies virus contains a virulence determinant.
J Gen Virol. 2000 Feb;81(Pt 2):415-20.
PMID: 10644840

Brack AR, Klupp BG, Granzow H, Tirabassi R, Enquist LW, Mettenleiter TC.
Role of the cytoplasmic tail of pseudorabies virus glycoprotein E in virion formation.
J Virol. 2000 May;74(9):4004-16.
PMID: 10756012

Card JP.
Pseudorabies virus and the functional architecture of the circadian timing system.
J Biol Rhythms. 2000 Dec;15(6):453-61.
PMID: 11106062

Dietz P, Klupp BG, Fuchs W, Kollner B, Weiland E, Mettenleiter TC.
Pseudorabies virus glycoprotein K requires the UL20 gene product for processing.
J Virol. 2000 Jun;74(11):5083-90.
PMID: 10799582

Ferrari M, Mettenleiter TC, Romanelli MG, Cabassi E, Corradi A, Dal Mas N, Silini R.
A comparative study of pseudorabies virus (PRV) strains with defects in thymidine kinase and glycoprotein genes.
J Comp Pathol. 2000 Aug-Oct;123(2-3):152-63.
PMID: 11032669

Ho TY, Wu SL, Hsiang CH, Chang TJ, Hsiang CY.
Identification of a DNA-binding domain and an active-site residue of pseudorabies virus DNase.
Biochem J. 2000 Mar 1;346 Pt 2:441-5.
PMID: 10677364

Husak PJ, Kuo T, Enquist LW.
Pseudorabies virus membrane proteins gI and gE facilitate anterograde spread of infection in projection-specific neurons in the rat.
J Virol. 2000 Dec;74(23):10975-83.
PMID: 11069992

Jin L, Schnitzlein WM, Scherba G.
Identification of the pseudorabies virus promoter required for latency-associated transcript gene expression in the natural host.
J Virol. 2000 Jul;74(14):6333-8.
PMID: 10864643

Kaelin K, Dezelee S, Masse MJ, Bras F, Flamand A.
The UL25 protein of pseudorabies virus associates with capsids and localizes to the nucleus and to microtubules.
J Virol. 2000 Jan;74(1):474-82.
PMID: 10590137

Klupp BG, Nixdorf R, Mettenleiter TC.
Pseudorabies virus glycoprotein M inhibits membrane fusion.
J Virol. 2000 Aug;74(15):6760-8.
PMID: 10888614

Mettenleiter TC.
Aujeszky's disease (pseudorabies) virus: the virus and molecular pathogenesis--state of the art, June 1999.
Vet Res. 2000 Jan-Feb;31(1):99-115.
PMID: 10726640

Nixdorf R, Klupp BG, Karger A, Mettenleiter TC.
Effects of truncation of the carboxy terminus of pseudorabies virus glycoprotein B on infectivity.
J Virol. 2000 Aug;74(15):7137-45.
PMID: 10888654

Smith BN, Banfield BW, Smeraski CA, Wilcox CL, Dudek FE, Enquist LW, Pickard GE.
Pseudorabies virus expressing enhanced green fluorescent protein: A tool for in vitro electrophysiological analysis of transsynaptically labeled neurons in identified central nervous system circuits.
Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9264-9.
PMID: 10922076

1999 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Bras F, Dezelee S, Simonet B, Nguyen X, Vende P, Flamand A, Masse MJ.
The left border of the genomic inversion of pseudorabies virus contains genes homologous to the UL46 and UL47 genes of herpes simplex virus type 1, but no UL45 gene.
Virus Res. 1999 Mar;60(1):29-40.
PMID: 10225272

Brideau AD, del Rio T, Wolffe EJ, Enquist LW.
Intracellular trafficking and localization of the pseudorabies virus Us9 type II envelope protein to host and viral membranes.
J Virol. 1999 May;73(5):4372-84.
PMID: 10196335

Brack AR, Dijkstra JM, Granzow H, Klupp BG, Mettenleiter TC.
Inhibition of virion maturation by simultaneous deletion of glycoproteins E, I, and M of pseudorabies virus.
J Virol. 1999 Jul;73(7):5364-72.
PMID: 10364283

Card JP, Enquist LW, Moore RY.
Neuroinvasiveness of pseudorabies virus injected intracerebrally is dependent on viral concentration and terminal field density.
J Comp Neurol. 1999 May 10;407(3):438-52.
PMID: 10320223

Cheung AK, Smith TA.
Analysis of the latency-associated transcript/UL1-3.5 gene cluster promoter complex of pseudorabies virus.
Arch Virol. 1999;144(2):381-91.
PMID: 10470261

Enquist LW.
Life beyond eradication: veterinary viruses in basic science.
Arch Virol Suppl. 1999;15:87-109.
PMID: 10470272

Favoreel HW, Nauwynck HJ, Pensaert MB.
Role of the cytoplasmic tail of gE in antibody-induced redistribution of viral glycoproteins expressed on pseudorabies-virus-infected cells.
Virology. 1999 Jun 20;259(1):141-7.
PMID: 10364498

Fernandez A, Menendez del Campo AM, Fernandez S, Camacho A, Castro JM, Tabares E.
Conversion of US3-encoded protein kinase gene from pseudorabies virus in a diploid gene located within inverted repeats by genetic recombination between the viral genome isomers.
Virus Res. 1999 Jun;61(2):125-35.
PMID: 10475082

Ho TY, Wu SL, Chang TJ, Hsiang CH, Chang SH, Hsiang CY.
Pseudorabies virus early protein 0 trans-activates the TATA-associated promoter by stimulating the transcription initiation.
Virus Res. 1999 May;61(1):77-86.
PMID: 10426211

Jin L, Scherba G.
Expression of the pseudorabies virus latency-associated transcript gene during productive infection of cultured cells.
J Virol. 1999 Dec;73(12):9781-8.
PMID: 10559288

Klupp BG, Mettenleiter TC.
Glycoprotein gL-independent infectivity of pseudorabies virus is mediated by a gD-gH fusion protein.
J Virol. 1999 Apr;73(4):3014-22.
PMID: 10074151

Kim JS, Enquist LW, Card JP.
Circuit-specific coinfection of neurons in the rat central nervous system with two pseudorabies virus recombinants.
J Virol. 1999 Nov;73(11):9521-31.
PMID: 10516061

Ono E, Tasaki T, Kobayashi T, Taharaguchi S, Nikami H, Miyoshi I, Kasai N, Arikawa J, Kida H, Shimizu Y.
Resistance to pseudorabies virus infection in transgenic mice expressing the chimeric transgene that represses the immediate-early gene transcription.
Virology. 1999 Sep 15;262(1):72-8.
PMID: 10489342

Smith GA, Enquist LW.
Construction and transposon mutagenesis in Escherichia coli of a full-length infectious clone of pseudorabies virus,an alphaherpesvirus.
J Virol. 1999 Aug;73(8):6405-14.
PMID: 10400733

Tirabassi RS, Enquist LW.
Mutation of the YXXL endocytosis motif in the cytoplasmic tail of pseudorabies virus gE.
J Virol. 1999 Apr;73(4):2717-28.
PMID: 10074118

Yang M, Card JP, Tirabassi RS, Miselis RR, Enquist LW.
Retrograde, transneuronal spread of pseudorabies virus in defined neuronal circuitry of the rat brain is facilitatedby gE mutations that reduce virulence.
J Virol. 1999 May;73(5):4350-9.
PMID: 10196333

Ono E, Watanabe S, Nikami H, Tasaki T, Kida H.
Pseudorabies virus (PRV) early protein 0 activates PRV gene transcription in combination with the immediate-early protein IE180 and enhances the infectivity of PRV genomic DNA.
Vet Microbiol. 1998 Oct;63(2-4):99-107.
PMID: 9850990

1998 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Boldogkoi Z, Braun A, Medveczky I, Glavits R, Gyuro B, Fodor I.
Analysis of the equalization of inverted repeats and neurovirulence using a pseudorabies virus mutant strain alteredat the Ul/Ir junction.
Virus Genes. 1998;17(1):89-98.
PMID: 9778792

Brideau AD, Banfield BW, Enquist LW.
The Us9 gene product of pseudorabies virus, an alphaherpesvirus, is a phosphorylated, tail-anchored type II membraneprotein.
J Virol. 1998 Jun;72(6):4560-70.
PMID: 9573219

Jons A, Dijkstra JM, Mettenleiter TC.
Glycoproteins M and N of pseudorabies virus form a disulfide-linked complex.
J Virol. 1998 Jan;72(1):550-7.
PMID: 9420258

Karger A, Schmidt J, Mettenleiter TC.
Infectivity of a pseudorabies virus mutant lacking attachment glycoproteins C and D.
J Virol. 1998 Sep;72(9):7341-8.
PMID: 9696830

Klupp BG, Baumeister J, Dietz P, Granzow H, Mettenleiter TC.
Pseudorabies virus glycoprotein gK is a virion structural component involved in virus release but is not required for entry.
J Virol. 1998 Mar;72(3):1949-58.
PMID: 9499048

Ono E, Taharaguchi S, Watanabe S, Nikami H, Shimizu Y, Kida H.
Suppression of pseudorabies virus replication by a mutant form of immediate-early protein IE180 repressing the viralgene transcription.
Vet Microbiol. 1998 Feb 28;60(2-4):107-17.
PMID: 9646443

Ono E, Watanabe S, Nikami H, Tasaki T, Kida H.
Pseudorabies virus (PRV) early protein 0 activates PRV gene transcription in combination with the immediate-early protein IE180 and enhances the infectivity of PRV genomic DNA.
Vet Microbiol. 1998 Oct;63(2-4):99-107.
PMID: 9850990

Pederson NE, Casey JT 2nd, Koslowski KM, Shaver PR.
The UL6 locus of pseudorabies virus and its homology to oncogenic herpesviruses.
Oncol Rep. 1998 Jan-Feb;5(1):115-9.
PMID: 9458304

Tirabassi RS, Enquist LW.
Role of envelope protein gE endocytosis in the pseudorabies virus life cycle.
J Virol. 1998 Jun;72(6):4571-9.
PMID: 9573220

Trybala E, Bergstrom T, Spillmann D, Svennerholm B, Flynn SJ, Ryan P.
Interaction between pseudorabies virus and heparin/heparan sulfate.Pseudorabies virus mutants differ in their interaction with heparin/heparan sulfate when altered for specific glycoprotein C heparin-binding domain.
J Biol Chem. 1998 Feb 27;273(9):5047-52.
PMID: 9478954

Watanabe S, Ono E, Nikami H, Kida H.
Promoter activity of sequence located upstream of the pseudorabies virus early protein 0 gene.
Vet Microbiol. 1998 Mar 15;61(1-2):7-19.
PMID: 9646461

Wu SL, Hsiang CY, Ho TY, Chang TJ.
Identification, expression, and characterization of the pseudorabies virus DNA-binding protein gene and gene product.
Virus Res. 1998 Jul;56(1):1-9.
PMID: 9784061

Wong ML, Yen YR.
Protein synthesis in pseudorabies virus-infected cells: decreased expression of protein kinase PKR, and effects of 2-aminopurine and adenine.
Virus Res. 1998 Aug;56(2):199-206.
PMID: 9783469

1997 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Dijkstra JM, Gerdts V, Klupp BG, Mettenleiter TC.
Deletion of glycoprotein gM of pseudorabies virus results in attenuation for the natural host.
J Gen Virol. 1997 Sep;78 ( Pt 9):2147-51.
PMID: 9292000

Dijkstra JM, Mettenleiter TC, Klupp BG.
Intracellular processing of pseudorabies virus glycoprotein M (gM) of strain Bartha lacks N-glycosylation.
Virology. 1997 Oct 13;237(1):113-22.
PMID: 9344913

Fuchs W, Klupp BG, Granzow H, Mettenleiter TC.
The UL20 gene product of pseudorabies virus functions in virus egress.
J Virol. 1997 Jul;71(7):5639-46.
PMID: 9188641

Garmendia AE, Lu Z, Tulman ER.
Discrete cleavage patterns of pseudorabies virus immediate early protein (IE180) seen in some cell lines upon extraction after cycloheximide reversal.
J Virol Methods. 1997 Mar;64(2):171-9.
PMID: 9079763

Granzow H, Weiland F, Jons A, Klupp BG, Karger A, Mettenleiter TC.
Ultrastructural analysis of the replication cycle of pseudorabies virus in cell culture: a reassessment.
J Virol. 1997 Mar;71(3):2072-82.
PMID: 9032339

Jons A, Gerdts V, Lange E, Kaden V, Mettenleiter TC.
Attenuation of dUTPase-deficient pseudorabies virus for the natural host.
Vet Microbiol. 1997 May;56(1-2):47-54.
PMID: 9228681

Jons A, Mettenleiter TC.
Green fluorescent protein expressed by recombinant pseudorabies virus as an in vivo marker for viral replication.
J Virol Methods. 1997 Jul;66(2):283-92.
PMID: 9255739

Lenk M, Visser N, Mettenleiter TC.
The pseudorabies virus UL51 gene product is a 30-kilodalton virion component.
J Virol. 1997 Jul;71(7):5635-8.
PMID: 9188640

Mulder WA, Pol JM, Gruys E, Jacobs L, De Jong MC, Peeters BP, Kimman TG.
Pseudorabies virus infections in pigs. Role of viral proteins in virulence, pathogenesis and transmission.
Vet Res. 1997;28(1):1-17.
PMID: 9172836

Knapp AC, Enquist LW.
Pseudorabies virus recombinants expressing functional virulence determinants gE and gI from bovine herpesvirus 1.1.
J Virol. 1997 Apr;71(4):2731-9.
PMID: 9060626

Knapp AC, Husak PJ, Enquist LW.
The gE and gI homologs from two alphaherpesviruses have conserved and divergent neuroinvasive properties.
J Virol. 1997 Aug;71(8):5820-7.
PMID: 9223471

Klupp BG, Fuchs W, Weiland E, Mettenleiter TC.
Pseudorabies virus glycoprotein L is necessary for virus infectivity but dispensable for virion localization of glycoprotein H.
J Virol. 1997 Oct;71(10):7687-95.
PMID: 9311852

Koslowski KM, Shaver PR, Wang XY, Tenney DJ, Pederson NE.
The pseudorabies virus UL28 protein enters the nucleus after coexpression with the herpes simplex virus UL15 protein.
J Virol. 1997 Dec;71(12):9118-23.
PMID: 9371568

Sawitzky D.
Transmission, species specificity, and pathogenicity of Aujeszky's disease virus.
Arch Virol Suppl. 1997;13:201-6.
PMID: 9413539

Schmidt J, Klupp BG, Karger A, Mettenleiter TC.
Adaptability in herpesviruses: glycoprotein D-independent infectivity of pseudorabies virus.
J Virol. 1997 Jan;71(1):17-24.
PMID: 8985318

Wong ML, Ho TY, Huang JH, Hsiang CY, Chang TJ.
Stimulation of type I DNA topoisomerase gene expression by pseudorabies virus.
Arch Virol. 1997;142(10):2099-105.
PMID: 9413519

1996 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Babic N, Klupp BG, Makoschey B, Karger A, Flamand A, Mettenleiter TC.
Glycoprotein gH of pseudorabies virus is essential for penetration and propagation in cell culture and in the nervous system of mice.
J Gen Virol. 1996 Sep;77 ( Pt 9):2277-85.
PMID: 8811028

Camacho A, Tabares E.
Characterization of the genes, including that encoding the viral proteinase, contained in BamHI restriction fragment 9 of the pseudorabies virus genome.
J Gen Virol. 1996 Aug;77 ( Pt 8):1865-74.
PMID: 8760438

Dezelee S, Bras F, Vende P, Simonet B, Nguyen X, Flamand A, Masse MJ.
The BamHI fragment 9 of pseudorabies virus contains genes homologous to the UL24,UL25, UL26, and UL 26.5 genes of herpes simplex virus type 1.
Virus Res. 1996 Jun;42(1-2):27-39.
PMID: 8806172

Dean HJ, Miller JM, Ackermann MR, Gao XY, Anderson LL, Jacobson CD, Cheung AK.
Replication and pathogenicity after intranasal and intracranial inoculation of swine with a recombinant pseudorabies virus containing a deletion at the UL/IR junction.
Virology. 1996 Sep 1;223(1):19-28.
PMID: 8806536

Dijkstra JM, Visser N, Mettenleiter TC, Klupp BG.
Identification and characterization of pseudorabies virus glycoprotein gM as a nonessential virion component.
J Virol. 1996 Aug;70(8):5684-8.
PMID: 8764089

Flynn SJ, Ryan P.
The receptor-binding domain of pseudorabies virus glycoprotein gC is composed of multiple discrete units that arefunctionally redundant.
J Virol. 1996 Mar;70(3):1355-64.
PMID: 8627651

Fuchs W, Klupp BG, Granzow H, Rziha HJ, Mettenleiter TC.
Identification and characterization of the pseudorabies virus UL3.5 protein, which is involved in virus egress.
J Virol. 1996 Jun;70(6):3517-27.
PMID: 8648685

Ho TY, Hsiang CY, Chang TJ.
Analysis of pseudorabies virus genes by cDNA sequencing.
Gene. 1996 Oct 10;175(1-2):247-51.
PMID: 8917106

Hsiang CY, Ho TY, Chang TJ.
Identification of a pseudorabies virus UL12 (deoxyribonuclease) gene.
Gene. 1996 Oct 24;177(1-2):109-13.
PMID: 8921854

Hsiang CY, Ho TY, Lin CH, Wu K, Chang TJ.
Analysis of upregulated cellular genes in pseudorabies virus infection: use of mRNA differential display.
J Virol Methods. 1996 Oct;62(1):11-9.
PMID: 8910644

Ishikawa K, Tsutsui M, Taguchi K, Saitoh A, Muramatsu M.
Sequence variation of the gC gene among pseudorabies virus strains.
Vet Microbiol. 1996 Apr;49(3-4):267-72.
PMID: 8734644

Jons A, Mettenleiter TC.
Identification and characterization of pseudorabies virus dUTPase.
J Virol. 1996 Feb;70(2):1242-5.
PMID: 8551588

Jons A, Granzow H, Kuchling R, Mettenleiter TC.
The UL49.5 gene of pseudorabies virus codes for an O-glycosylated structural protein of the viral envelope.
J Virol. 1996 Feb;70(2):1237-41.
PMID: 8551587

Karger A, Mettenleiter TC.
Identification of cell surface molecules that interact with pseudorabies virus.
J Virol. 1996 Apr;70(4):2138-45.
PMID: 8642635

Mettenleiter TC.
Immunobiology of pseudorabies (Aujeszky's disease).
Vet Immunol Immunopathol. 1996 Nov;54(1-4):221-9.
PMID: 8988868

Mulder W, Pol J, Kimman T, Kok G, Priem J, Peeters B.
Glycoprotein D-negative pseudorabies virus can spread transneuronally via direct neuron-to-neuron transmission in its natural host, the pig, but not after additional inactivation of gE or gI.
J Virol. 1996 Apr;70(4):2191-200.
PMID: 8642642

Sawitzky D, Voigt A, Zeichhardt H, Habermehl KO.
Glycoprotein B (gB) of pseudorabies virus interacts specifically with the glycosaminoglycan heparin.
Virus Res. 1996 Mar;41(1):101-8.
PMID: 8725106

Tonomura N, Ono E, Shimizu Y, Kida H.
Negative regulation of immediate-early gene expression of pseudorabies virus by interferon-alpha.
Vet Microbiol. 1996 Dec;53(3-4):271-81.
PMID: 9008338

Trybala E, Bergstrom T, Spillmann D, Svennerholm B, Olofsson S, Flynn SJ, Ryan P.
Mode of interaction between pseudorabies virus and heparan sulfate/heparin.
Virology. 1996 Apr 1;218(1):35-42.
PMID: 8615039

Watanabe S, Ono E, Shimizu Y, Kida H.
Mapping of transregulatory domains of pseudorabies virus early protein 0 and identification of its dominant-negative mutant.
Arch Virol. 1996;141(6):1001-9.
PMID: 8712918

1995 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Baumeister J, Klupp BG, Mettenleiter TC.
Pseudorabies virus and equine herpesvirus 1 share a nonessential gene which is absent in other herpesviruses and located adjacent to a highly conserved gene cluster.
J Virol. 1995 Sep;69(9):5560-7.
PMID: 7637001

Berthomme H, Monahan SJ, Parris DS, Jacquemont B, Epstein AL.
Cloning, sequencing, and functional characterization of the two subunits of the pseudorabies virus DNA polymeraseholoenzyme: evidence for specificity of interaction.
J Virol. 1995 May;69(5):2811-8.
PMID: 7707503

Card JP, Dubin JR, Whealy ME, Enquist LW.
Influence of infectious dose upon productive replication and transynaptic passage of pseudorabies virus in rat central nervous system.
J Neurovirol. 1995 Dec;1(5-6):349-58.
PMID: 9222377

Dean HJ, Cheung AK.
A deletion at the UL/IR junction reduces pseudorabies virus neurovirulence.
J Virol. 1995 Feb;69(2):1334-8.
PMID: 7815517

Glazenburg KL, Moormann RJ, Kimman TG, Gielkens AL, Peeters BP.
Genetic recombination of pseudorabies virus: evidence that homologous recombination between insert sequences is less frequent than between autologous sequences.
Arch Virol. 1995;140(4):671-85.
PMID: 7794111

Hanssens FP, Nauwynck HJ, Mettenlieter TC.
Role of glycoprotein gD in the adhesion of pseudorabies virus infected cells and subsequent cell-associated virusspread.
Arch Virol. 1995;140(10):1855-62.
PMID: 7503685

Karger A, Saalmuller A, Tufaro F, Banfield BW, Mettenleiter TC.
Cell surface proteoglycans are not essential for infection by pseudorabies virus.
J Virol. 1995 Jun;69(6):3482-9.
PMID: 7745695

Ono E, Sakoda Y, Taharaguchi S, Watanabe S, Tonomura N, Kida H, Shimizu Y.
Inhibition of pseudorabies virus replication by a chimeric trans-gene product repressing transcription of the immediate-early gene.
Virology. 1995 Jun 20;210(1):128-40.
PMID: 7793065

Sams JM, Jansen AS, Mettenleiter TC, Loewy AD.
Pseudorabies virus mutants as transneuronal markers.
Brain Res. 1995 Jul 31;687(1-2):182-90.
PMID: 7583303

Standish A, Enquist LW, Miselis RR, Schwaber JS.
Dendritic morphology of cardiac related medullary neurons defined by circuit-specific infection by a recombinant pseudorabies virus expressing beta-galactosidase.
J Neurovirol. 1995 Dec;1(5-6):359-68.
PMID: 9222378

Taharaguchi S, Ono E, Yamada S, Shimizu Y, Kida H.
Mapping of a functional region conferring nuclear localization of pseudorabies virus immediate-early protein.
Arch Virol. 1995;140(10):1737-46.
PMID: 7503675

Watanabe S, Ono E, Shimizu Y, Kida H.
Pseudorabies virus early protein 0 transactivates the viral gene promoters.
J Gen Virol. 1995 Nov;76 ( Pt 11):2881-5.
PMID: 7595399

1994 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

De Wind N, Peeters BP, Zuderveld A, Gielkens AL, Berns AJ, Kimman TG.
Mutagenesis and characterization of a 41-kilobase-pair region of the pseudorabies virus genome: transcription map, search for virulence genes, and comparison with homologs of herpes simplex virus type 1.
Virology. 1994 May 1;200(2):784-90.
PMID: 8178460

Dean HJ, Cheung AK.
Identification of the pseudorabies virus UL4 and UL5 (helicase) genes.
Virology. 1994 Aug 1;202(2):962-7.
PMID: 8030256

Fuchs W, Bauer B, Mettenleiter TC, Rziha HJ.
A novel intergenic site for integration and expression of foreign genes in the genome of pseudorabies virus.
J Virol Methods. 1994 Jan;46(1):95-105.
PMID: 8175950

Gasperik J, Lesko J, Csabayova M, Golais F.
Pseudorabies virus growth factor can be resolved into two active components.
Acta Virol. 1994 Apr;38(2):117-20.
PMID: 7976863

Glazenburg KL, Elgersma-Hooisma M, Briaire J, Voermans J, Kimman TG, Gielkens AL, Moormann RJ.
Vaccine properties of pseudorabies virus strain 783 are not affected by a deletion of 71 base pairs in the promoter/enhancer region of the viral immediate early gene.
Vaccine. 1994 Sep;12(12):1097-100.
PMID: 7998419

Jacobs L, Mulder WA, Priem J, Pol JM, Kimman TG.
Glycoprotein I of pseudorabies virus (Aujeszky's disease virus) determines virulence and facilitates penetration of the virus into the central nervous system of pigs.
Acta Vet Hung. 1994;42(2-3):289-300.
PMID: 7810422

Klupp BG, Baumeister J, Karger A, Visser N, Mettenleiter TC.
Identification and characterization of a novel structural glycoprotein in pseudorabiesvirus, gL.
J Virol. 1994 Jun;68(6):3868-78.
PMID: 8189524

Kimman TG, De Wind N, De Bruin T, de Visser Y, Voermans J.
Inactivation of glycoprotein gE and thymidine kinase or the US3-encoded protein kinase synergistically decreases in vivo replication of pseudorabies virus and the induction of protective immunity.
Virology. 1994 Dec;205(2):511-8.
PMID: 7975253

Mettenleiter TC.
Pseudorabies (Aujeszky's disease) virus: state of the art. August 1993.
Acta Vet Hung. 1994;42(2-3):153-77.
PMID: 7810409

Mettenleiter TC, Spear PG.
Glycoprotein gB (gII) of pseudorabies virus can functionally substitute for glycoprotein gB in herpes simplex virus type 1.
J Virol. 1994 Jan;68(1):500-4.
PMID: 8254761

Yamada S, Shimizu M.
Isolation and characterization of mutants of pseudorabies virus with deletion in the immediate-early regulatory gene.
Virology. 1994 Mar;199(2):366-75.
PMID: 8122367

Yamada S, Shimizu M.
Pseudorabies virus immediate-early regulatory protein IE180 expressed by recombinant baculovirus is functional.
Virology. 1994 Jul;202(1):491-5.
PMID: 8009863

1993 References selected from the molecular subset of MEDLINE: --------------------------------------------------------------

Berthomme H, Jacquemont B, Epstein A.
The pseudorabies virus host-shutoff homolog gene: nucleotide sequence and comparison with alphaherpesvirus protein counterparts.
Virology. 1993 Apr;193(2):1028-32.
PMID: 8384744

Card JP, Rinaman L, Lynn RB, Lee BH, Meade RP, Miselis RR, Enquist LW.
Pseudorabies virus infection of the rat central nervous system: ultrastructural characterization of viral replication, transport, and pathogenesis.
J Neurosci. 1993 Jun;13(6):2515-39.
PMID: 8388923

Dean HJ, Cheung AK.
A 3' coterminal gene cluster in pseudorabies virus contains herpes simplex virus UL1,UL2, and UL3 gene homologs and a unique UL3.5 open reading frame.
J Virol. 1993 Oct;67(10):5955-61.
PMID: 8396663

Edson CM.
Phosphorylation of neurotropic alphaherpesvirus envelope glycoproteins: herpes simplex virus type 2 gE2 and pseudorabies virus gI.
Virology. 1993 Jul;195(1):268-70.
PMID: 8391184

Hanssens FP, Nauwynck HJ, Pensaert MB.
Involvement of membrane-bound viral glycoproteins in adhesion of pseudorabies virus-infected cells.
J Virol. 1993 Aug;67(8):4492-6.
PMID: 8392594

Heffner S, Kovacs F, Klupp BG, Mettenleiter TC.
Glycoprotein gp50-negative pseudorabies virus: a novel approach toward a nonspreading live herpesvirus vaccine.
J Virol. 1993 Mar;67(3):1529-37.
PMID: 8382308

Jacobs L, Mulder WA, Van Oirschot JT, Gielkens AL, Kimman TG.
Deleting two amino acids in glycoprotein gI of pseudorabies virus decreases virulence and neurotropism for pigs, but does not affect immunogenicity.
J Gen Virol. 1993 Oct;74 ( Pt 10):2201-6.
PMID: 8409943

Jansen AS, Farwell DG, Loewy AD.
Specificity of pseudorabies virus as a retrograde marker of sympathetic preganglionic neurons: implications for transneuronal labeling studies.
Brain Res. 1993 Jul 16;617(1):103-12.
PMID: 8397044

Karger A, Mettenleiter TC.
Glycoproteins gIII and gp50 play dominant roles in the biphasic attachment of pseudorabies virus.
Virology. 1993 Jun;194(2):654-64.
PMID: 8389078

Mettenleiter TC, Saalmuller A, Weiland F.
Pseudorabies virus protein homologous to herpes simplex virus type 1 ICP18.5 is necessary for capsid maturation.
J Virol. 1993 Mar;67(3):1236-45.
PMID: 8382292

Whealy ME, Card JP, Robbins AK, Dubin JR, Rziha HJ, Enquist LW.
Specific pseudorabies virus infection of the rat visual system requires both gI and gp63 glycoproteins.
J Virol. 1993 Jul;67(7):3786-97.
PMID: 8389905