Human herpesvirus 1 (HSV-1)
Gene Image Map
Human herpesvirus 1, strain 17, commonly called herpes simplex virus 1, was sequenced by the McGeoch
laboratory and published in a series of papers from 1985-1988. These are included in a
comprehensive set of references from Medline (1980-6/2000),
HSV-1 References.
Human herpesvirus 1 is a member of the Herpesviridae family. General properties
are available here,
Herpesviridae Properties.
Interesting genome information and properties specific to HSV-1 are available here,
HSV-1 Properties.
An overview map of the genome and information summary is available through
the
Gene Image Map.
The newest version of this map clearly depicts coterminal and overlapping
genes, genes coding on opposite strands and repeats,
all of which are common in the tightly packed genomes of herpesviruses.
A double-stranded interactive visualization tool, called
BugBrowser , is now available.
The core information in this database is the table of annotated records, one for each of
90 genes. Each gene record is identified by a gene id, HHVONE001-HHVONE077 (some with extensions to total 90).
Seventy-eight of the genes are unique and six (gamma34.5, Orf-P, Orf-O, alpha0, alpha4,
and the LAT) appear twice in the genome, once in each copy of the inverted repeats. Simple summaries of specific information are available below in the Predefined Database Searches and contain links to the complete gene record.
The power of a relational database is demonstrated in the ability to search it's information.
We provide five search tools, each with different characteristics. The
Basic Search
allows a simple query of many fields for a text term. The
Intermediate Search
allows the user to search specific tables, to search a range of molecular
weights or isoelectric points and to search the protein or nucleotide sequences for simple patterns. The
Advanced SQL Search
allows those who understand Structured Query Language to construct cross
table and more specific queries and the
Protein Motif Search
allows searching protein sequences for sophisticated amino acid patterns.
Repeat Search queries the repeat table for previously located nucleotide repeats.
User Defined Database Searches
Basic Search
Intermediate Search
Advanced SQL Search
Sequence Search
Protein Motif Search
Repeat Search
Predefined Database Searches
Definition Table
Functional Classes Table
EC Table
PDB Table
Essential Genes Table
Posttranslational Modifications Table
Protein-Protein Interactions Table
Repeat Tables
Tandem
Terminal
Inverted
All
Cellular Homolog Table
Visualization
Gene Image Map
Genome Visualization Tool - BugBrowser
