The Chlamydia pneumoniae circular genome of 1.23 Mb was sequenced in 1999 by teams at Stanford and UC-Berkeley (with funding by Incyte Pharmaceuticals, Inc.). The strain was CWL029. The key publication describing this newly sequenced genome is "Comparative Genomics of Chlamydia pneumoniae and C. trachomatis" by S. Kalman, et al., Nature Genetics 21: 385-389, 1999. Approximately 800 additional references pertaining to Chlamydial research can be extracted from the Molecular Subset of MEDLINE (C.trachomatis references). C. pneumoniae is not an STD pathogen, however it is included in this collection of bacterial genomic databases for comparative purposes. A comparison of the C. trachomatis and C. pneumoniae genomes is presented in the bacterial analysis section (Chlamydia proteome comparisions). Complex rearrangements as well as horizontal transmissions characterize the genomes of chlamydia (in contrast to the relatively conserved synteny of the Mycoplasmas).
The core information in this relational database is the table of annotated records for each gene. CPn0001 through CPn1073 identify the genes in C.pneumoniae. (In comparison the C.trachomatis genome encodes 875 proteins.) To these records, analyses and links are appended, and from these, tables and graphics are dynamically constructed. Because C.pneumoniae is not a primary subject of this project, some annotations and analyses have not been undertaken.
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