Inventory of Treponema pallidum ABC transporters


 
NBD protein
MSD protein
SBP Protein
 
 
 
NBD1 NBD2 MSD1 TM EAA MSD2 TM EAA SBP1 SBP2 Domain Subfamily Function
A. Importers
TP0035
 
TP0036
7
-2
 
 
 
TP0034
 
3
8
Zn/Mn?
TP0581
 
TP0580
6
-2
TP0582
6
-2
TP0585
 
2
9
peptide?
TP0142
 
TP0143
9
-2
 
 
 
TP0144
 
3
5a Thiamine ?
TP0164
 
TP0165
5
-2
TP0166
6
-2
TP0163
 
2
8
manganese?
TP0300 TP0300 TP0301
9
-1
TP0302
7
-2
TP0298
 
4
1
galactosides?
TP0321 TP0321 TP0322
9
-2
TP0323
8
-2
TP0319
 
4
1
galactosides?
TP0652
 
TP0653
7
0
TP0654
7
0
TP0655
 
2
5a Spermidine / Putrescine
 
 
 
 
 
 
 
 
 
 
 
 
 
TP0685 TP0685 TP0686
7
-2
 
 
 
TP0684
 
9
1
D-Galactose/D-Ribose?
 
 
 
 
 
 
 
 
TP0545
 
 
1
D-galactose/ D-glucose
 
 
 
 
 
 
 
 
 
 
 
 
 
TP0804
 
 
 
 
 
 
 
TP0737
 
 
5a oligo-saccharide
 
 
TP0075
6
-1
TP0076
5
0
TP0074
 
 
5a Maltose/ sn-Glycerol-3-phosphate 
 
 
 
 
 
 
 
 
 
 
 
 
 
TP0120
 
TP0119
4
0
 
 
 
TP0821???
 
3
2 or 4  peptide or amino acid
 
 
 
 
 
 
 
 
TP0308 TP0309
 
4
amino acid??
B.Exporters
TP0964
 
TP0963
4
-2
TP0962
5
-2
 
 
2
9
antibiotic
TP0227
 
TP0226
5
-2
 
 
 
 
 
3
12
?
TP0611
 
 
 
 
 
 
 
 
 
 
None ?
TP0838 TP0838 TP0840???
7
-2
 
 
 
 
 
9
3
macrolide?
TP0881
 
TP0880
7
-2
 
 
 
 
 
3
7a Na+
TP0786
 
 
 
 
 
 
 
 
 
 
 
 

The ABC transporters are split into importers and exporters. For each ABC transporter, the nucleotide-binding domains (NBD1 and NBD2), the membrane-spanning domains (MSD1 and MSD2), and the solute-binding proteins (SBP1 and SBP2) are reported. The functions were assigned based on the similarity searches against Genbank.

TM: Transmembrane segments predicted with the PHD htm program

EAA motifs predicted with the Pattern Search.

Blue: Newly uncovered fusion protein.

Red: Newly uncovered ABC transporter components