Treponema pallidum mgl operon has been assigned a putative function(glucose import). An active promoter 135 bp upstream of tp-mglB is believed to direct mRNA synthesis for this operon. Furthermore, by analogy with E. coli MglB which interacts with the sensory transducer Trg to induce a chemotactic response, T. pallidum also contains a homolog of E. coli Trg or other methyl-accepting chemotaxis proteins. The existence of a mgl operon in T. pallidum thus may have important implications with respect to T. pallidum survival, tissue dissemination, and sensory transduction during virulence expression. (Gene 1996 Oct 24;177(1-2):115-21 A mgl-like operon in Treponema pallidum, the syphilis spirochete. Porcella SF, Popova TG, Hagman KE, Penn CW, Radolf JD, Norgard MV PMID: 8921855, UI: 97080510)