The mkdom and XDOM programs have been used to analyze the domain organizations of the NBD proteins. The analysis revealed three types of organization in Neisseria gonorrhoeae: (1) the dimeric ATP-binding proteins (NBD-NBD) (e.g. NG0870, NG1573, NG0764 and NG0781), (2) the membrane/ATP-binding domain associations (MSD-NBD) (e.g., NG1439, NG2165, and NG1732), and (3) the isolated NBD.

Black box: Walker A, B motif

Green box: MSD domain