The mkdom and XDOM programs have been used to analyze the domain organizations of the NBD proteins. The analysis revealed three types of organization in Mycoplasma genitalium: (1) the dimeric ATP-binding proteins (NBD-NBD) (e.g. MG119); (2) the membrane/ATP-binding domain associations (MSD-NBD)(e.g. MG014, MG015 and MG390), and (3) the isolated NBD.

Black box: Walker A motif

Red box: signature and Walker B motif