Inventory of Chlamydia trachomatis ABC transporters


 
NBD protein
MSD protein
SBP Protein
 
 
 
NBD1 NBD2 MSD1 TM EAA MSD2 TM EAA SBP1 SBP2 Domain Subfamily Function
A. Importers
CT068
 
CT069
7
-2
CT070
10
-2
CT067
 
2
8
manganese?
CT130
 
CT129
4
0
 
 
 
CT381
 
3
4
amino acid
 
 
 
 
 
 
 
 
CT486
 
 
4
glutamine
CT180
 
CT854
3
 
 
 
 
 
 
3
5c nitrate?
CT201 CT202 CT200
6
-2
CT199
6
-2
CT198
 
1
2
oligopeptide
CT689 CT690
 
 
 
 
 
 
 
 
1
2
 
 
 
CT479
5
-2
CT478
5
-2
CT480
 
 
2
oligopeptide?
 
 
 
 
 
 
 
 
CT175
 
 
2
dipeptide?
CT416
 
CT417
7
-2
 
 
 
CT415
 
3
8
Zn/Mn?
 
 
 
 
 
 
 
 
 
 
 
 
 
B.Exporters
CT152
 
CT151
4
-2
 
 
 
 
 
3
9
antibiotic
CT264
 
CT264
4
-2
 
 
 
 
 
5
6
multidrug
CT685
 
CT684
 
-2
CT686
1
-2
 
 
2
None ?
CT348 CT348
 
 
 
 
 
 
 
 
 
3
macrolide?
CT653
 
 
 
 
 
 
 
 
 
 
7c antibiotic

The ABC transporters are split into importers and exporters. For each ABC transporter, the nucleotide-binding domains (NBD1 and NBD2), the membrane-spanning domains (MSD1 and MSD2), and the solute-binding proteins (SBP1 and SBP2) are reported. The functions were assigned based on the similarity searches against Genbank.

TM: Transmembrane segments predicted with the PHD htm program

EAA motifs predicted with the Pattern Search.

Blue: Newly uncovered fusion protein.

Red: Newly uncovered ABC transporter components