Plasma membrane organization of the 4 protein domains of the main types of ABC transporters encountered in Actinobacillus actinomycetemcomitans and gene organization.


Domain Type

NBD protein

MSD protein

SBP Protein

Function

NBD1

NBD2

MSD1

MSD2

SBP1

SBP2

1

AA00933

AA00934

AA00935

AA00936

AA00932

ribose

1

AA02898

AA02899

AA02893

AA02895

AA02891

AA02892

oilgopeptide

1

AA02225

AA02226

AA02220

AA02224

??

2

AA00061

AA00059

AA00058

AA00057

heme

2

AA00799

AA00796

AA00798

AA00795

iron(III)

2

AA00858

AA00854

AA00855

AA00856

arginine

2

AA01656

AA01649

AA01650

AA01657

AA01658

maltose/maltodextrin

2

AA01824

AA01825

AA01826

AA01827

iron(III)

2

AA01947

AA01948

AA01950

AA01952

spermidine/putrescine(?)

2

AA02550

AA02551

AA02552

AA02549

iron (chelated)

2

AA02718

AA02719

AA02720

AA02721

spermidine/putrescine

2

AA01616

AA01615

AA01618

??

2

AA02440

AA02438

AA02439

??

3

AA00415

AA00416

AA00417

D-methionine

3

AA01524

AA01525

AA01526

amino acid

3

AA01779

AA01780

AA01781

molybdenum

3

AA01867

AA01866

AA01865

thiamin

3

AA02152

AA02153

AA02154

iron(III)

3

AA02324

AA02325

AA02327

toluene(?)

3

AA02353

AA02352

AA02352

glycine/betaine/carnitine/choline

3

AA01422

AA01423

??

3

AA01820

AA01818

zinc

3

AA02642

AA02643

??

5

AA00591

AA00591

??

5

AA01961

AA01961

lipid A

5

AA02080

AA02080

??

6

AA01509

AA01510

AA01509

AA01510

??

7

AA01684

AA01685

AA01682

AA01681

molybdenum

7

A02145

AA02146

AA02144

iron(III)

8

AA00700

AA00699

AA00696

AA00698

iron(III)

8

AA01051

AA01050

AA01048

iron(III)

8

AA01645

AA01644

AA01642

iron(III)

9

AA00207

AA00207

AA00208

AA00209

D-ribose

9

AA00751

AA00751

AA00753

AA00750

galactoside

9

AA01456

AA01456

AA01457

AA01455

D-xylose

9

AA02786

AA02786

AA02785

AA02787

AA02788

ribose

9

AA02140

AA02140

AA02141

??


Plasma membrane organization of the four protein domains of the main types of ABC transporters encountered in Actinobacillus actinomycetemcomitans and organization of the chromosomal region containing the genes encoding one particular member. The membrane-spanning domains (MSDs) and the two nucleotide-binding domains (NBDs) are depicted by ovals and triangles, respectively. When fused, domains are linked together using a large connecting area.