Porphyromonas gingivalis
  Proteome and Gene Cluster Comparisons  
Gene Id COG Id Definition Comment
PG0229  K  N utilization substance protein A (NusA) (transcription termination-antitermination factor) (transcriptional terminator)  
PG0230  J  translation initiation factor IF-2
PG0232  R  ABC transporter subunit PG0234 does not exist.
PG0233  R  ABC transporter ATPase
PG0235  R  conserved hypothetical protein (possible ABC transporter related membrane protein)
PG0288  J 50S ribosomal protein L21  
PG0289  J 50S ribosomal protein L27
PG0342  J  50S ribosomal protein L13  
PG0343  J  30S ribosomal protein S9
PG0344  J  30S ribosomal protein S2
PG0345  J  elongation factor TS (EF-TS)
PG0353  "J,E"  elongation factor Tu  
PG0354  N hypothetical protein(possible translocase secE subunit)
PG0355  K  transcription antiterminator
PG0356  J  50S ribosomal protein L11
PG0357  J  50S ribosomal protein L1
PG0358  J  50S ribosomal protein L10
PG0359  J  50S ribosomal protein L7/L12
PG0360  K  DNA-directed RNA polymerase subunit beta
PG0361  K  DNA-directed RNA polymerase subunit beta'
PG0382  O  ATP-dependent ClpX-related protease PG0383 does not exist.
PG0384  O  ATP-dependent clp protease proteolytic subunit (endopeptidase CLP)
PG0474  O  60 kD chaperonin (protein cpn60) (GroEL protein) (heat shock protein 60)  
PG0475  O  10 kDa chaperonin/heat shock protein (protein cpn10) (protein GroES)
PG0482 E F carbamoyl-phosphate synthase small subunit PG 0483 does not exist.
PG0484 E F glutamine-hydrolyzing carbamoyl-phosphate synthase (CPSase)
PG0519  M  phospho-N-acetylmuramoyl pentapeptide transferase  
PG0520  M  N-acetylymuramoyl-L-alanine-D-glutamate ligase
PG0522  M  GLCNAC transferase (UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)-pyrophosphoryl-undecaprenol Nacetylglucosamine transferase)  
PG0523  M  UDP-N-acetylmuramate--alanine ligase
PG0525 D cell division protein ftsA  
PG0526 D cell division protein ftsZ
PG0537  J  30S ribosomal protein S6 PG0539 does not exist.
PG0538  J  30S ribsomal protein S18
PG0540  J  50S ribosomal protein L9
PG0802  C  cytochrome d oxidase subunit II  
PG0803  C  cytochrome d oxidase subunit I
PG0886  J  50S ribosomal protein L20  
PG0887  J  translation initiation factor 3 (IF-3)
PG0888 J threonyl-tRNA synthetase
PG0959 C electron transfer flavoprotein beta-subunit  
PG0960 C electron-transfer flavoprotein alpha-subunit
PG1044 C conserved hypothetical protein  
PG1045 C conserved hypothetical protein (containing ferredoxin-like domain)
PG1168 C NAD(P)+ transhydrogenase subunit alpha  
PG1169 C probable NAD(P) transhydrogenase subunit alpha (pyridine nucleotide transhydrogenase subunit alpha) (nicotinamide nucleotide transhydrogenase subunit alpha)
PG1170 C NAD(P) transhydrogenase subunit beta
PG1223 D rod shape-determining protein  
PG1224 M penicillin binding protein 2
PG1367 M dTDP-4-dehydrorhamnose 3,5-epimerase rfbD  
PG1368 M glucose-1-phosphate thymidyltransferase rfbA
PG1532  P  ABC transporter (SBP domain); adhesin  
PG1533  P  ABC transporter/NBD protein for possibly Zn/Mn
PG1575  C  ATP synthase subunit A (V-type ATPase subunit A)  
PG1576  C  ATP synthase subunit B (V-type ATPase subunit B)
PG1577  C  H+-transporting ATP synthase subunit D
PG1578  C  vacuolar ATPase subunit I
PG1579  C  putative H+-transporting ATP synthase  subunit K
PG1657  J  ribosome recycling factor (ribosome releasing factor)  
PG1658  F  uridylate kinase (uridine monophosphate kinase) (UMP kinase)
PG1666  J  50S ribosomal protein L17  
PG1667  K  RNA polymerase alpha subunit (DNA-directed RNA polymerase alpha subunit) (transcriptase alpha chain)
PG1668 J  30S ribosomal protein S4
PG1669  J  30S ribosomal protein S11
PG1670  J  30S ribosomal protein S13
PG1673  N  preprotein translocase SecY
PG1673.1  J  50S ribosomal protein L15
PG1674  J  30S ribosomal protein S5
PG1675  J  50S ribosomal protein L18
PG1676  J  50S ribosomal protein L6
PG1677  J  30S ribosomal protein S8
PG1678  J  30S ribosomal protein S14
PG1679  J  50S ribosomal protein L5
PG1680  J  50S ribosomal protein L24
PG1681  J  50S ribosomal protein L14
PG1682  J  30S ribosomal protein S17
PG1683  J  50S ribosomal protein L16
PG1684 J  30S ribosomal protein S3
PG1685  J  50S ribosomal protein L22
PG1686  J  30S ribosomal protein S19
PG1687  J  50S ribosomal protein L2
PG1688  J  50S ribosomal protein L23
PG1689  J  50S ribosomal protein L4
PG1690  J  50S ribosomal protein L3
PG1691  J  30S ribosomal protein S10
PG1692  J  elongation factor G protein
PG1693  J  30S ribosomal protein S7
PG1694  J  30S ribosomal protein S12
PG1906 H, C Na+-translocating NADH-quinone reductase nqr6  
PG1907  C  Na+-translocating NADH-quinone reductase subunit Nqr5 (sodium-translocating NADH dehydrogenase)
PG1908  C  Na+-translocating NADH-quinone reductase subunit Nqr4 (sodium-translocating NADH dehydrogenase)
PG1909    Na+-translocating NADH-quinone reductase gamma subunit (sodium-translocating NADH dehydrogenase subunit nqr3)
PG1910  S  NADH dehydrogenase (ubiquinone)
PG1911  I Na+-translocating NADH-ubiquinone oxidoreductase alpha subunit nqrA

Not only is it useful to find which orthologous clusters are shared between multiple bacteria, but also to determine which orthologous clusters in Porphyromonas gingivalis are shared by bacteria capable of being sexually transmitted (since P. gingivalis is most closely related to this group of sequenced bacteria) but not found in bacteria such as Escherichia coli, Haemophilus ducreyi, or Streptococcus pyogenes. This analysis helps to identify the gene clusters responsible for the pathogens' unique characteristics, e.g. genes unique to mucosal obligate anaerobes. Note that only genes found in clusters are included in this comparison.

It is also useful to determine which genes in Porphyromonas gingivalis are shared by Chlamydia tracomatis, a bacterium capable of being sexually transmitted, but not shared by Escherichia coli. This analysis helps to identify the genes responsible for the pathogens' unique characteristics, e.g. genes unique to mucosal obligate anaerobes.