Regulatory
pathway
|
Activating
signal
|
Signal
transduction mechanism
|
Regulon
members
|
Physiological
roles
|
sigmaE
|
Misfolded
OM or periplasmic proteins
|
Relief
of inhibitory interacions between the membrane-anchored sigma factor RseA and sigmaE
|
Envelope
folding factor FkpA, envelope protease DegP, rpoE, rseABC, rpoH, virulence
factors, unidentified members
|
Ensures
proper OMP folding
|
Cpx
|
IM
associated aggregates of misfolded protein
|
Alterations
in phosphotransfer reactions between the HK CpxA and RR CpxR
|
Envelope
folding factors (DsbA, PpiA, PpiD), envelope protease DegP, cpxRA, cpxP,
virulence factors, unidentified members
|
Ensures
properly timed biogenesis of pili, others?
|