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Treponema pallidum Search Results

Record: 1 of 1  
MiniMap IGR747 IGR745 IGR748 IGR743 IGR744 IGR742 IGR746 ndk, - TP1010 pth, - TP1011 sigA,rpoD, - TP1012 gpsA, - TP1009 tpn39b,bmp, - TP1016 alaS, - TP1017 TP1014 nrdA, - TP1008 groES, - TP1013 ndk, - TP1010 pth, - TP1011 sigA,rpoD, - TP1012 gpsA, - TP1009 tpn39b,bmp, - TP1016 alaS, - TP1017 TP1014 nrdA, - TP1008 groES, - TP1013 ndk, - TP1010 pth, - TP1011 sigA,rpoD, - TP1012 gpsA, - TP1009 tpn39b,bmp, - TP1016 alaS, - TP1017 TP1014 nrdA, - TP1008 nusB, - TP1015 nusB, - TP1015 groES, - TP1013
* Calculated from Protein Sequence

Gene ID: TP1013

DNA Molecule Name:

Genbank ID:

Gene Name:

chaperonin (heat shock protein GroES)

Gene Start:

Gene Stop:

Gene Length:

Molecular Weight*:


Net Charge*:


Functional Class:
Cellular processes; Chaperones  

Pathway: pathway table

Secondary Evidence:
Houry WA.
Mechanism of substrate recognition by the chaperonin GroEL.
Biochem Cell Biol. 2001;79(5):569-77.
PMID: 11716298

Song JL, Wynn RM, Chuang DT.
Interactions of GroEL/GroES with a heterodimeric intermediate during alpha 2beta 2 assembly of mitochondrial branched-chain alpha-ketoacid dehydrogenase. cis capping of the native-like 86-kDa intermediate by GroES.
J Biol Chem. 2000 Jul;275(29):22305-12.
PMID: 10764784

Chuang JL, Wynn RM, Song JL, Chuang DT.
GroEL/GroES-dependent reconstitution of alpha2 beta2 tetramers of humanmitochondrial branched chain alpha-ketoacid decarboxylase. Obligatory interaction of chaperonins with an alpha beta dimeric intermediate.
J Biol Chem. 1999 Apr;274(15):10395-404.
PMID: 10187829

Chua-Intra B, Peerapakorn S, Davey N, Jurcevic S, Busson M, Vordermeier HM, Pirayavaraporn C, Ivanyi J.
T-cell recognition of mycobacterial GroES peptides in Thai leprosy patients and contacts.
Infect Immun. 1998 Oct;66(10):4903-9.
PMID: 9746595

In Bacillus stearothermophilus, this protein binds to Cpn60 in the
presence of Mg-ATP and suppress the ATPase activity of the latter.
It is induced by heat shock.

Blast Summary:  PSI-Blast Search
Gapped BLAST revealed several significant hits to chaperonin GroES
proteins. For example residues 5-87 are 51% similar to CH10_BACST,
chaperonin GroES protein of Bacillus stearothermophilus,(L10132).

COGS Summary:  COGS Search
BeTs to 13 clades of COG0234
COG name: Co-chaperonin GroES (HSP10)
Functional Class:? O
The phylogenetic pattern of COG0234 is ----yqvcebrhujgpolinx
Number of proteins in this genome belonging to this COG is 1

Blocks Summary:  Blocks Search
Residues 30-82, 3-55, 37-88, 23-75, and 29-81 represent significant
(98%) hits to block BL00681, Chaperonins cpn10 proteins.

ProDom Summary:  Protein Domain Search
Residues 24-78 are 54% similar to chaperonin of CH10_THEBR.

Paralogs:  Local Blast Search
There is no evidence of paralogs in T. pallidum.

Pfam Summary:  Pfam Search
Residues 2 to 88 (E-value = 4.3e-34) place TP1013 in the Cpn10 family which is described as Chaperonin 10 Kd subunit (PF00166)

PDB Hit:
gi|1942632|pdb|1LEP|A Mycobacterium leprae

Gene Protein Sequence:

Gene Nucleotide Sequence:  Sequence Viewer

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