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Haemophilus ducreyi Search Results

Record: 1 of 1  
MiniMap IGR7 IGR6 IGR9 IGR8 IGR3 IGR5 IGR1.1 IGR4 IGR1 IGR2 atpE, - HD0005 HD0003 atpF, - HD0006 HD2037 atpH, - HD0007 gidB, - HD0002 atpA, - HD0004 atpG, - HD0009 atpD, - HD0010 atpA, - HD0008 gidA, - HD0001 atpE, - HD0005 HD0003 atpF, - HD0006 HD2037 atpH, - HD0007 gidB, - HD0002 atpA, - HD0004 atpG, - HD0009 atpD, - HD0010 atpA, - HD0008 gidA, - HD0001 atpE, - HD0005 HD0003 atpF, - HD0006 atpH, - HD0007 gidB, - HD0002 atpA, - HD0004 atpG, - HD0009 atpD, - HD0010 atpA, - HD0008 gidA, - HD0001
* Calculated from Protein Sequence

Gene ID: HD0005

DNA Molecule Name:

Genbank ID:

Gene Name:

ATP synthase F0, subunit c

Gene Start:

Gene Stop:

Gene Length:

Molecular Weight*:


Net Charge*:


Functional Class:
Energy metabolism; ATP-proton motive force interconversion  

Pathway: pathway table
ATP synthesis
Flagellar assembly
Type III secretion system

Primary Evidence:

Secondary Evidence:
Nielsen,J., Hansen,F.G., Hoppe,J., Friedl,P. and von Meyenburg,K. The nucleotide sequence of the atp genes coding for the F0 subunits a, b, c and the F1 subunit delta of the membrane bound ATP synthase of Escherichia coli.
Mol. Gen. Genet. 184 (1), 33-39 (1981)
Medline: 82147764.

Kanazawa,H., Mabuchi,K., Kayano,T., Noumi,T., Sekiya,T. and Futai,M.
Nucleotide sequence of the genes for F0 components of the proton-translocating ATPase from Escherichia coli: prediction of the primary structure of F0 subunits.
Biochem. Biophys. Res. Commun. 103 (2), 613-620 (1981)
Medline: 82134799.

Cain,B.D. and Simoni,R.D.
Impaired proton conductivity resulting from mutations in the a subunit of F1F0 ATPase in Escherichia coli.
J. Biol. Chem. 261 (22), 10043-10050 (1986)
Medline: 86278048.

Kumamoto,C.A. and Simoni,R.D.
Genetic evidence for interaction between the a and b subunits of the F0 portion of the Escherichia coli proton translocating ATPase.
J. Biol. Chem. 261 (22), 10037-10042 (1986)
Medline: 86278047.

Cain,B.D. and Simoni,R.D. Proton translocation by the F1F0ATPase of Escherichia coli. Mutagenic analysis of the a subunit. J. Biol. Chem. 264 (6), 3292-3300 (1989)
Medline: 89123453.

Yamada,H., Moriyama,Y., Maeda,M. and Futai,M. Transmembrane topology of Escherichia coli H(+)-ATPase (ATP synthase) subunit a. FEBS Lett. 390 (1), 34-38 (1996)
Medline: 96314544.

Valiyaveetil,F.I. and Fillingame,R.H.
Transmembrane topography of subunit a in the Escherichia coli F1F0 ATP synthase.
J. Biol. Chem. 273 (26), 16241-16247 (1998)
Medline: 98298136.

The N-terminal half of this short protein matched only weakly to the N-terminal half of a few ATPase proteins in GenBank. The C-terminal half was comparatively well-conserved.

See also chains of the F1 subunit: atpA (alpha chain), HD0008; atpB (beta chain), HD0010; atpG (gamma chain), HD0009; atpD (delta chain), HD0007; atpE (epsilon chain), HD0011.

In addition, see the other chains of the F0 subunit of this ATPase: atpF (B chain), HD0006, and atp6 (A chain), HD0004.

Note: Check the start codon. Hits started at residue 12, a methionine.

Blast Summary:  PSI-Blast Search
Many significant matches in gapped BLAST to ATP synthase, subunit c proteins: H. influenzae (16272431, 1168602), Pseudomonas aeruginosa PA01 (15600752), and Vibrio cholerae (15642762), among others.

COGS Summary:  COGS Search
BeTs to 7 clades of COG0636
COG name: FoF1-type ATP synthase c subunit/Vacuolar ATPase/archaeal ATP synthase K subunit
Functional Class: C
The phylogenetic pattern of COG0636 is AmtkYqvcebrhujgpolinx
Number of proteins in this genome belonging to this COG is 1

Blocks Summary:  Blocks Search
***** IPB000454 (Eubacterial and plasma membrane ATP synthase subunit C) with a combined E-value of 4e-17.
    IPB000454    15-68

ProDom Summary:  Protein Domain Search
Residues 35-75 are 97% similar to a (LIPID-BINDING C SYNTHASE CHAIN) protein domain (PD186061) which is seen in ATPL_HAEIN.

Residues 33-79 are 63% similar to a (C LIPID-BINDING ION SUBUNIT) protein domain (PD390276) which is seen in Q9JR78_NEIMB.

Paralogs:  Local Blast Search
HD0005 has no significant similarity (blastp p-value < 1e-3) to any other gene in this genome.

Pfam Summary:  Pfam Search
Residues 7 to 76 (E-value = 1.9e-24) place HD0005 in the ATP-synt_C family which is described as ATP synthase subunit C (PF00137)

PDB Hit:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:

Gene Nucleotide Sequence:  Sequence Viewer

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