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Mycoplasma genitalium




Three different base composition analyses were performed on the coding regions in the Mycoplasma genitalium genome: G+C content (%), genome signature, and codon bias. The genome signature and codon bias were determined according to methods established by Samuel Karlin (Trends Microbiol. 2001 Jul;9(7):335-43.). The codon bias of each gene was calculated against both the whole genome and the set of ribosomal proteins. Ribosomal proteins in microbial genomes are typically encoded by genes that have a codon usage distinct from the genome mean. Ribosomal proteins and genes with codon usage patterns similar to them have been linked to gene expression (Karlin S, Mrazek J. J Bacteriol. 2000 Sep;182(18):5238-50.). Genes that deviate from the genome, but not the set of ribosomal proteins are considered putative highly expressed, whereas genes that deviate from both the genome mean and the ribosomal proteins are considered putative alien genes. Each of these analyses is displayed below as well as a measure of deviation from the genome mean value. The table is ordered by gene ID numbers, which reflect genome position. Thus, gene clusters with deviant base composition can be identified. These clusters may have been the result of a lateral gene transfer event and are catalogued in the Genomic Island Table. Genes that are 3 or more standard deviations from the mean in any of the base composition metrics are catalogued the Deviant Gene Table. .




Metric Mean Value Standard Deviation
 G+C Content (%) 31.61   3.67  
 Genome Signature 120   49  
 Codon Bias (Genome) 281   96  
 Codon Bias (Ribosomal) 313   87 


Standard deviations are indicated by a number of stars:
*       difference from mean is greater than 1.5  standard deviations
**      difference from mean is greater than 2    standard deviations
***     difference from mean is greater than 3    standard deviations
****    difference from mean is greater than 4    standard deviations
*****   difference from mean is greater than 5    standard deviations





 Gene       G+C        Genome      Codon Bias   Codon Bias     Database
  ID 	  Content(%)  Signature     (Genome)    (Ribosomal)    Definition
-------   -------    -----------   ----------   -----------    --------------------
MG001      25.22 *      154           343           416        DNA polymerase III beta subunit
MG002       27.2        182           247           328        DnaJ-related heat shock protein
MG003      35.28         65           188           203        DNA gyrase subunit B (DNA topoisomerase IV subunit
                                                               B)
MG004      33.01         91           185           281        DNA gyrase subunit A (topoisomerase IV subunit A)
MG005       30.7         99           156           231        seryl-tRNA synthetase
MG006      30.32        112           284           368        thymidylate kinase
MG007       24.8 *      129           323           437        possible DNA polymerase III subunit delta'
MG008      26.02 *      115           235           339        thiophene and furan oxidation proteins
MG009      27.74        148           286           389        conserved hypothetical protein
MG010      26.61        137           320           402        DNA primase
MG011       25.2 *      153           269           375        hypothetical protein
MG012      28.74        141           279           341        ribosomal protein S6 modification protein
MG013      27.84         98           316           389        5,10-methylenetetrahydrofolate dehydrogenase/5,10-
                                                               methenyltetrahydrofolate cyclohydrolase
MG014      28.95         92           183           261        ABC transporter; MSD-NBD fusion protein
MG015      29.82        114           218           311        ABC transporter protein; possible MSD-NBD fusion
                                                               protein
MG016      27.58        231 **        306           348        conserved hypothetical protein
MG017      24.81 *       64           329           367        hypothetical protein
MG018      28.88        140           233           321        helicase
MG019      32.65         99           207           277        heat shock protein
MG020       30.3        108           230           333        proline iminopeptidase
MG021      28.45         89           195           260        methionyl-tRNA synthetase
MG022      30.34        166           285           307        RNA polymerase
MG023      31.83         98           233           312        fructose-bisphosphate aldolase
MG024       29.7         61           233           319        probable GTP-binding protein
MG025      29.19        124           224           295        hypothetical protein (possible glycosyltransferase)
MG026      31.58        102           314           373        elongation factor P
MG027       28.7        130           320           387        hypothetical protein
MG028      28.69         81           283           365        hypothetical protein
MG029      28.85        142           306           384        hypothetical protein
MG030      33.66        135           315           367        uracil phosphoribosyltransferase
MG031       30.6         79           105           203        DNA polymerase III alpha subunit (polC1)
MG032      31.63         67           188           285        conserved hypothetical protein
MG033       35.3        145           245           296        glycerol uptake facilitator protein
MG034      32.86         60           335           352        thymidine kinase
MG035      29.39         80           219           310        histidyl-tRNA synthetase
MG036      30.18        108           170           260        aspartyl-tRNA synthetase
MG037      30.37         77           185           272        pre-B cell enhancing factor precursor
MG038      33.79         92           161           225        glycerol kinase
MG039       30.9         83           178           249        glycerol-3-phospate dehydrogenase
MG040      32.54         80           189           263        membrane lipoprotein; possible ABC solute binding
                                                               protein
MG041      33.71        174           375           444        phosphocarrier protein HPr
MG042      29.28         96           167           246        spermidine/putrescine transport ATP-binding protein
                                                               of ABC system
MG043      31.35         88           284           316        spermidine/putrescine transport system permease of
                                                               ABC system
MG044      29.23        115           315           349        spermidine/putrescine transport system permease of
                                                               the ABC transport system
MG045      31.19        123           200           270        conserved hypothetical protein; possible ABC
                                                               transporter solute binding protein
MG046      32.38         89           234           315        O-sialoglycoprotein endopeptidase
MG047      32.29         94           231           303        S-adenosylmethionine synthetase
MG048      33.26         84           254           284        signal recognition particle protein
MG049      32.19        171           234           259        purine nucleoside phosphorylase
MG050      32.88        156           247           318        deoxyribose-phosphate aldolase
MG051      30.09        103           233           330        thymidine phosphorylase
MG052         30        103           300           317        cytidine deaminase
MG053      31.58         63           234           283        phosphomannomutase
MG054       30.8         78           229           301        transcription antitermination protein NusG
MG055      28.73        146           343           351        hypothetical protein
MG055.1    34.72        312 ***       644 ***       577 ***    ribosomal protein L33, putative
MG055.2    25.72 *      159           375           389        Mycoplasma-specific hypothetical protein
MG056      27.92        105           243           313        conserved hypothetical protein (possible
                                                               methyltransferase)
MG057      27.34        171           270           332        conserved hypothetical protein
MG058         33         72           231           280        phosphoribosylpyrophosphate synthetase
MG059      28.28        111           326           410        small protein B
MG060      27.38         34           281           387        hypothetical protein (possible glycosyltransferase)
MG061      33.12        107           198           252        hexosephosphate transport protein
MG062      33.09        119           168           250        fructose-permease II ABC component
MG063      28.24        101           221           301        1-phosphofructokinase
MG064      29.71         50           114           210        conserved hypothetical protein; possible MSD element
                                                               in the ABC transport system
MG065       30.4         48           147           204        ABC transporter, ATP-binding protein
MG066      32.92         70           131           187        transketolase
MG067      30.81         85           187           249        Mycoplasma-specific conserved hypothetical protein
MG068      30.45        115           211           259        Mycoplasma-specific conserved hypothetical protein
MG069      35.87         48           169           223        PTS system, glucose-specific II ABC protein
MG070      34.15         93           268           215        30S Ribosomal protein S2
MG071      33.75         55           127           178        cation-transporting P-ATPase
MG072      35.81         63           172           148        preprotein translocase subunit (secA)
MG073      34.04         62           165           179        excinuclease ABC subunit B
MG074      28.71        266 **        432 *         400        hypothetical protein
MG075      30.86         66           130           193        hypothetical protein
MG076      29.23        233 **        328           346        hypothetical protein
MG077      34.07         90           295           294        oligopeptide transport system permease of the ABC
                                                               system
MG078      35.55        108           215           245        oligopeptide transport system permease of the ABC
                                                               system
MG079      34.41         91           251           270        oligopeptide ABC transporter, ATP-binding protein
MG080      31.92         78           187           151        oligopeptide ABC transporter, ATP-binding protein
MG081      35.28        174           300           290        50S ribosomal protein L11
MG082      33.78         97           179           231        50S ribosomal protein L1
MG083      33.51         86           278           332        peptidyl-tRNA hydrolase
MG084       33.1         93           245           191        conserved hypothetical protein (probable PP-loop
                                                               ATPase)
MG085       32.9         61           231           202        probable HPr kinase
MG086      32.11        114           242           283        prolipoprotein diacylglyceryl transferase
MG087      38.85 *      140           356           348        30S ribosomal protein S12
MG088      37.63 *      138           296           258        30S ribosomal protein S7
MG089      36.14         51           177           218        translation elongation factor EF-G
MG090      34.46         79           294           253        30S ribosomal protein S6
MG091         35        127           296           332        single-stranded DNA-binding protein
MG092      35.24        171           388           366        30S ribosomal protein S18
MG093      32.89        208 *         274           279        50S ribosomal protein L9
MG094      33.93         71           219           205        DNA helicase (dnaB)
MG095      31.83         48           169           210        hypothetical protein
MG096       33.4         88           188           239        conserved hypothetical protein
MG097      32.38        121           280           324        uracil DNA glycosylase
MG098      31.38         80           220           237        conserved hypothetical protein (possible glu-tRNA
                                                               amidotransferase, subunit C)
MG099      32.22         68           193           259        amidase (glu-tRNA amidotransferase, subunit A)
MG100      31.73         79           201           254        Glu-tRNAGln amidotransferase B subunit/ PET112
                                                               homolog
MG101      33.93        102           360           345        Mycoplasma-specific conserved hypothetical protein
MG102      33.02         85           190           241        thioredoxin reductase
MG103      27.74        153           246           236        conserved hypothetical protein (basic)
MG104      33.29         59           158           186        VACB protein homolog (ribonuclease II family)
MG105         31        105           341           344        conserved hypothetical protein (basic)
MG106      32.45        129           272           321        formylmethionine deformylase (polypeptide
                                                               deformylase)
MG107       30.5        131           333           370        guanylate kinase
MG108      29.36         92           197           263        protein phosphatase 2C homolog
MG109       32.6         80           209           246        protein serine,threonine kinase
MG110      28.95         92           263           338        conserved hypothetical protein (basic)
MG111      31.41         76           210           253        phosphoglucose isomerase B
MG112      31.26        138           290           330        D-ribulose-5-phosphate 3 epimerase
MG113      33.04         59           199           234        asparaginyl-tRNA synthetase
MG114      31.78        109           282           336        CDP-diacylglycerol--glycerol-3-phosphate 3-
                                                               phosphatidyltransferase
                                                               (phosphatidylglycerophosphate synthase)
MG115      32.07        169           435 *         474 *      hypothetical protein
MG116      30.01        114           270           310        Mycoplasma-specific conserved hypothetical protein
                                                               (M. genitalium predicted coding region MG116)
MG117      30.84        113           243           295        Mycoplasma-specific conserved hypothetical protein
                                                               (M. genitalium predicted coding region MG117)
MG118      30.49         99           279           332        UDP-glucose 4-epimerase
MG119      32.21         57           182           212        sugar ABC transporter, ATP-binding protein
MG120      32.76         68           225           247        possible ribose/galactose transport system permease
                                                               protein
MG121      35.29        150           292           278        ribose/galactose ABC transporter, permease
MG122      33.43         85           192           159        DNA topoisomerase I
MG123      28.87        117           183           214        conserved hypothetical protein (basic)
MG124      33.66        133           340           349        thioredoxin
MG125      29.59        100           220           274        conserved hypothetical protein (basic)/ possible
                                                               hydrolase
MG126      30.64         74           182           228        tryptophanyl-tRNA synthetase
MG127      31.72        160           347           344        conserved hypothetical protein (basic)
MG128      33.72         92           275           244        conserved hypothetical protein (basic)
MG129      28.21        196 *         393           422        probable PTS glucose-specific permease
MG130       30.1         92           190           219        conserved hypothetical protein (basic)
MG131      27.03        262 **        527 **        522 **     hypothetical protein
MG132      32.15         97           319           338        HIT-like protein
MG133      29.97        128           211           250        Mycoplasma-specific conserved hypothetical protein
                                                               (basic) (M. genitalium predicted coding region
                                                               MG133)
MG134         33        151           343           334        Mycoplasma-specific conserved hypothetical protein
MG135      31.43         76           277           305        Mycoplasma-specific conserved hypothetical protein
                                                               (basic)
MG136      32.72         77           183           223        lysyl-tRNA synthetase
MG137      31.35        126           255           252        UDP-galactopyranose mutase
MG138       33.5        122           268           246        GTP-binding protein (possible membrane protein)
MG139      34.27         99           191           172        conserved hypothetical protein (possible Zn-
                                                               dependent hydrolase)
MG140      33.21         80           187           145        ATP-binding protein (possible DNA helicase related
                                                               protein)
MG141      32.58         82           152           166        N-utilization substance protein A homolog
MG142      34.89         66           216           231        translation initiation factor 2
MG143      32.74        172           316           353        Mycoplasma-specific conserved hypothetical protein
                                                               (basic)
MG144      32.14         81           184           203        Mycoplasma-specific conserved hypothetical protein
                                                               (basic)
MG145      30.61        147           262           280        riboflavin kinase/ possible FMN adenyltransferase
MG146      31.68         95           234           202        hemolysin-like protein (CBS domain protein)
MG147      32.18        127           283           274        Mycoplasma-specific hypothetical protein; possible
                                                               MSD protein in AB transport system
MG148      29.91        116           249           214        conserved hypothetical protein; possible MSD element
                                                               in ABC transport system
MG149      33.45        118           194           275        Mycoplasma-specific protein; possible ABC solute
                                                               binding protein, putative lipoprotein
MG149.1    30.19        122           446 *         423        Mycoplasma-specific hypothetical protein
MG150      36.48        147           447 *         383        30S ribosomal protein S10
MG151      38.91 *      112           328           265        50S ribosomal protein L3
MG152      36.81        170           436 *         414        50S ribosomal protein L4
MG153      34.91        192           454 *         415        50S ribosomal protein L23
MG154      40.47 **     138           325           277        50S ribosomal protein L2
MG155       36.4        169           503 **        452 *      30S ribosomal protein S19
MG156      36.57        110           360           316        50S ribosomal protein L22
MG157      39.05 **      97           382           286        30S ribosomal protein S3
MG158       41.3 **     119           353           304        50S ribosomal protein L16
MG159      32.67        222 **        382           366        50S ribosomal protein L29
MG160      37.25 *      188           478 **        489 **     30S ribosomal protein S17
MG161       38.8 *      149           372           364        50S ribosomal protein L14
MG162       35.8        129           398           334        50S ribosomal protein L24
MG163      36.67         91           354           322        50S ribosomal protein L5
MG164      42.62 ***    256 **        621 ***       624 ***    30S ribosomal protein S14
MG165      34.04        161           406           365        30S ribosomal protein S8
MG166      34.96        189           307           228        50S ribosomal protein L6
MG167      35.94        188           418           360        50S ribosomal protein L18
MG168      39.02 **     113           391           327        30S ribosomal protein S5
MG169         38 *      224 **        375           336        50S ribosomal protein L15
MG170      39.65 **     131           342           268        preprotein translocase secY subunit
MG171      34.11        154           380           396        adenylate kinase
MG172      35.75        121           337           313        methionine aminopeptidase
MG173      37.62 *      274 ***       583 ***       547 **     translation initiation factor IF1
MG174      38.74 *      249 **        694 ****      592 ***    50S ribosomal protein L36
MG175      39.52 **     133           515 **        475 *      30S ribosomal protein S13
MG176      42.49 **     120           454 *         409        30S ribosomal protein S11
MG177      37.91 *       72           379           319        DNA-directed RNA polymerase alpha chain
MG178      36.31        165           456 *         412        50S ribosomal protein L17
MG179      35.64        102           312           266        ABC transporter ATP-binding protein; possible cobalt
                                                               transport ATP-binding protein O homolog
MG180      37.06        108           294           250        ABC transporter ATP-binding protein
MG181      35.56        109           301           268        conserved hypothetical protein; possible MSD element
                                                               in the ABC transport system
MG182      34.84        107           331           321        pseudouridine synthetase/ tRNA-pseudouridine
                                                               synthase I
MG183      32.24         66           192           166        oligoendopeptidase F
MG184      30.39        167           257           226        adenine-specific DNA modification methylase
MG185      32.67         81           159           190        Mycoplasma-specific protein; possible ABC solute
                                                               binding protein, putative lipoprotein
MG186      36.53         89           336           303        Mycoplasma-specific hypothetical protein / putative
                                                               lipoprotein
MG187      33.85        142           279           261        ABC transporter ATP-binding protein
MG188      37.69 *      107           390           343        ABC transporter permase protein/ probable sn-
                                                               Glycerol-3-phosphate transport system permease
MG189      36.03         90           357           310        possible ABC transporter permease
MG190       33.7        114           316           304        conserved hypothetical protein (29 kDa protein, MgPa
                                                               operon)
MG191      39.89 **     142           304           218        Mycoplasma-specific attachment protein, MgPa operon,
                                                               adhesin P1
MG192      40.72 **     114           324           273        Mycoplasma-specific conserved hypothetical protein
                                                               (114 kDa protein, MgPa operon)
MG194      33.14        107           262           275        phenylalanyl-tRNA synthetase alpha-subunit
MG195      32.42         91           254           207        phenylalanyl-tRNA synthetase beta chain
MG196      35.93        185           474 **        428        translation initiation factor IF3
MG197      40.68 **     304 ***       651 ***       633 ***    50S ribosomal protein L35
MG198      35.22        100           329           319        50S ribosomal protein L20
MG199      32.34        150           342           382        ribonuclease HII
MG200      38.99 **     128           332           281        DnaJ-related heat shock protein
MG201      35.48         76           407           348        grpE-related heat shock protein
MG202      36.34        121           422           369        Mycoplasma-specific hypothetical protein
MG203       36.6         85           326           240        DNA topoisomerase IV subunit B (gyrase B)
MG204      33.72         61           239           191        DNA topoisomerase IV subunit A
MG205       34.6         89           339           253        heat shock gene negative repressor HRCA
MG206      33.02        110           266           209        ABC excinuclease subunit C
MG207      34.64        163           429 *         381        conserved hypothetical protein
MG208      33.67        101           366           335        Mycoplasma-specific hypothetical protein
MG209      34.42         88           240           213        pseudouridine synthase (uracil hydrolase)
MG210      29.83        152           391           346        prolipoprotein signal peptidase
MG210.1    35.16        129           432 *         401        Mycoplasma-specific hypothetical protein
MG211      33.56        169           371           349        Mycoplasma-specific hypothetical protein
MG211.1    33.04        160           407           396        conserved hypothetical protein (probable acyl-
                                                               carrier protein synthase)
MG212      32.21        119           277           270        1-acyl-sn-glycerol-3-phosphate acyltransferase
MG213      32.13         67           237           192        conserved hypothetical protein
MG214      35.27        111           295           298        conserved hypothetical protein
MG215      36.43        105           311           285        6-phosphofructokinase
MG216      36.29         64           280           234        pyruvate kinase
MG217      34.14        164           260           215        Mycoplasma-specific conserved hypothetical protein
                                                               (possible proline-rich P65 protein)
MG218      34.16        129           209           131        adhesin accessory
MG218.1    35.84         99           264           235        conserved hypothetical protein
MG219      34.01        226 **        375           397        hypothetical protein (basic)
MG220      33.66        108           475 **        532 **     Mycoplasma-specific hypothetical protein (basic)
MG221      35.28        160           427 *         403        conserved hypothetical protein
MG222      33.44         85           300           261        conserved hypothetical protein (basic)
MG223      31.14         83           324           291        Mycoplasma-specific conserved hypothetical protein
                                                               (basic)
MG224      33.33         70           249           186        FtsZ-related cell division protein
MG225      33.47        129           254           222        amino acid permease (predicted)
MG226      32.39        128           206           221        amino acid permease of the ABC transport system
MG227      33.22         78           241           248        thymidylate synthase
MG228      30.21        100           310           321        dihydrofolate reductase
MG229      37.35 *       88           353           292        ribonucleoside diphosphate reductase beta subunit
MG230      34.42        171           352           298        NrdI-related protein
MG231      35.41         89           236           189        ribonucleoside diphosphate reductase alpha subunit
MG232         37        161           461 *         361        50S ribosomal protein L21
MG233      35.35        142           435 *         445 *      conserved hypothetical protein (YsxB-related)
MG234      40.71 **     103           438 *         376        50S ribosomal protein L27
MG235       36.2         81           294           312        endonuclease IV
MG236      35.24        105           393           328        Mycoplasma-specific hypothetical protein
MG237      31.86        167           269           230        Mycoplasma-specific hypothetical protein
MG238      32.13         70           192           182        FKBP-type peptidyl-prolyl cis-trans isomerase
                                                               (trigger factor)
MG239      36.69        116           266           182        ATP-dependent protease La-1 (Lon)
MG240      31.96         96           319           306        conserved hypothetical protein
MG241      28.39         65           162           198        conserved hypothetical protein
MG242      28.25        103           164           197        conserved hypothetical protein
MG243      29.31        191           360           411        Mycoplasma-specific hypothetical protein
MG244      28.97         83           170           228        DNA helicase II
MG245      26.06 *      162           279           323        conserved hypothetical protein
MG246      31.79         90           250           272        conserved hypothetical protein
MG247      30.26        118           334           353        conserved hypothetical protein
MG248      27.52        156           300           380        conserved hypothetical protein
MG249      34.47        115           217           227        RNA polymerase sigma A factor
MG250      29.65         69           152           194        DNA primase
MG251      32.44         76           150           199        glycyl-tRNA synthetase
MG252      31.27         54           245           221        rRNA methylase
MG253      31.07         92           222           258        cysteinyl-tRNA synthetase
MG254      30.35         48           144           222        NAD-dependent DNA ligase
MG255      29.32         98           243           246        Mycoplasma-specific hypothetical protein
MG255.1    30.25        182           419           426        Mycoplasma-specific hypothetical protein
MG256      29.43         85           269           258        Mycoplasma-specific hypothetical protein
MG257      37.11 *      162           448 *         400        50S ribosomal protein L31
MG258      34.73         72           248           263        peptide chain release factor 1 (RF-1)
MG259      28.58         97           167           227        protoporphyrinogen oxidase homolog
MG260      31.94         84           139           221        Mycoplasma-specific conserved hypothetical protein
                                                               (basic)
MG261      29.37         31           137           199        DNA polymerase III alpha subunit (polC2)
MG262      30.58         79           243           295        5'-3' exonuclease (including N-terminal domain of
                                                               PolI)
MG262.1    28.76         72           243           332        formamidoprymidine-DNA glycosylase
MG263       31.5        117           263           297        conserved hypothetical protein
MG264      30.64        160           312           299        conserved hypothetical protein
MG265      29.62        104           229           287        conserved hypothetical protein
MG266      32.62         56           131           207        leucyl-tRNA synthetase
MG267      33.04        169           375           377        Mycoplasma-specific hypothetical protein
MG268      31.73        100           255           259        conserved hypothetical protein (possible deoxypurine
                                                               kinase subunit)
MG269      33.14        127           236           252        conserved hypothetical protein
MG270      33.04         80           249           279        lipoate-protein ligase
MG271      35.45        112           235           218        dihydrolipoamide dehydrogenase component E3
MG272      35.85         77           196           268        dihydrolipoamide acetyltransferase component E2
MG273      39.57 **      63           269           296        pyruvate dehydrogenase component E1 beta subunit
MG274      37.71 *       78           279           258        pyruvate dehydrogenase component E1 alpha subunit
MG275      35.43        109           234           198        NADH oxidase
MG276       36.3        133           339           318        adenine phosphoribosyltransferase
MG277      33.85        105           166           135        Mycoplasma-specific hypothetical protein (integral
                                                               membrane protein)
MG278      31.44         41           194           141        guanosine-3',5'-bis(diphosphate) 3'-
                                                               pyrophosphohydrolase
MG279      29.82         91           285           285        Mycoplasma-specific hypothetical protein
MG280      32.12        126           231           293        Mycoplasma-specific hypothetical protein
MG281      34.89         98           224           249        Mycoplasma-specific hypothetical protein
MG282      36.44        104           315           310        transcription elongation factor (transcript cleavage
                                                               factor greA)
MG283      31.88        102           183           230        prolyl-tRNA synthetase
MG284       29.8        198 *         400           424        Mycoplasma-specific hypothetical protein
MG285      32.18        109           273           292        Mycoplasma-specific hypothetical protein
MG286      28.06         63           282           361        Mycoplasma-specific hypothetical protein
MG287      26.19        199 *         372           469 *      possible acyl carrier protein
MG288      28.26        108           240           298        conserved hypothetical protein
MG289      27.99        109           285           361        high affinity transport system protein P37
MG290      26.53         97           299           376        ATP-binding transport protein (P29), ATP-binding
                                                               protein
MG291      26.15        120           223           300        P69 transport permease protein
MG291.1    26.57        170           337           407        conserved hypothetical protein
MG292      28.15         61           177           276        alanyl-tRNA synthetase
MG293      27.73        156           263           279        probable glycerolphosphoryl diester
                                                               phosphodiesterase
MG294         32        113           166           225        conserved hypothetical protein (possible permease)
MG295      28.25         86           239           348        probable tRNA (5-methylaminoethyl-2-thiouridylate)-
                                                               methyltransferase
MG296      28.42        156           293           350        Mycoplasma-specific hypothetical protein
MG297      30.54        106           204           276        cell division protein FtsY homolog
MG298      32.42         62           113           169        conserved hypothetical protein
MG299      34.69         95           225           265        phosphate acetyltransferase
MG300      33.73        121           206           235        phosphoglycerate kinase
MG301       36.7        107           251           286        glyceraldehyde-3-phosphate dehydrogenase
MG302      27.87        136           186           252        conserved hypothetical protein; possible MSD element
                                                               in the ABC transport system
MG303      29.23        112           219           258        ABC transporter; predicted NBD protein
MG304      31.49         59           251           271        ABC transporter; possible NBD protein
MG305      36.97         75           241           235        DnaK protein (heat shock 70kD protein)
MG306      31.21         92           199           189        conserved hypothetical protein; possible MSD element
                                                               of the ABC transport system
MG307      31.24         73           136           230        Mycoplasma-specific protein; possible ABC transport
                                                               solute binding protein
MG308      28.46         85           194           246        probable ATP-dependent RNA helicase
MG309      30.61         73           128           221        Mycoplasma-specific protein; possible solute binding
                                                               protein in ABC transport system
MG310      31.47         80           277           323        predicted acyltransferase/hydrolase with the
                                                               alpha/beta hydrolase fold (putative esterase/lipase
                                                               1)
MG311      33.17        197 *         337           319        30S ribosomal protein S4
MG312      32.31        140           156           216        cytadherence high molecular weight protein
                                                               (cytadherence-accessory protein)
MG313      29.35        175           268           324        Mycoplasma-specific hypothetical protein (basic)
MG314      31.98         66           198           202        conserved hypothetical protein
MG315      27.16        122           243           329        conserved hypothetical protein
MG316      27.55        137           190           266        conserved hypothetical protein
MG317      34.22        171           192           261        cytadherence high molecular weight protein
                                                               (cytadherence-accessory protein)
MG318      39.64 **     158           262           231        cytadhesin P32
MG319      33.15        107           330           314        Mycoplasma-specific hypothetical protein
MG320      32.17        128           275           282        Mycoplasma-specific  protein; possible MSD element
                                                               in the ABC transport system.
MG320.1    43.68 ***    214 *         708 ****      633 ***    hypothetical protein
MG321      35.47         92           160           159        Mycoplasma-specific protein; possible solute binding
                                                               protein in the ABC transport system
MG322      33.03         94           145           194        K+ and Na+ transport (uptake) protein; possible MSD
                                                               element of ABC transport system
MG323      33.19         87           290           249        K+ or Na+ transport (uptake) protein
MG323.1    28.87        158           262           284        Mycoplasma-specific hypothetical protein
MG324      33.15         69           195           221        XAA-pro aminopeptidase
MG325      32.08        251 **        597 ***       619 ***    50S ribosomal protein L33
MG326      30.51        112           234           260        conserved hypothetical protein
MG327      29.98        117           252           318        putative esterase/lipase 2
MG328      29.28        166           196           246        conserved hypothetical protein (acidic)
MG329      31.92         77           205           280        conserved hypothetical GTP-binding protein
MG330      30.72        112           261           331        cytidylate kinase
MG331      25.63 *      167           282           355        Mycoplasma-specific hypothetical protein
MG332       30.4         64           310           377        conserved hypothetical protein
MG333      33.07        110           268           304        acyl carrier protein phosphodiesterase, putative,
                                                               authentic frameshift
MG334      28.63         87           188           276        valyl-tRNA synthetase
MG335       27.4        100           320           431        conserved hypothetical protein (probable GTP-binding
                                                               protein)
MG335.1    31.96        218 **        534 **        565 **     conserved hypothetical protein
MG335.2    25.12 *      102           212           302        conserved hypothetical protein (possible
                                                               transferase)
MG336      26.88        121           249           334        nitrogen fixation (nifS like) protein
MG337      23.19 **     179           403           502 **     Mycoplasma-specific hypothetical protein
MG338      29.43         89           196           304        lipoprotein, putative
MG339       30.2        130           243           346        RecA protein
MG340      34.73         56           167           167        DNA-directed RNA polymerase, subunit beta prime
MG341      34.56         82           126           159        DNA-directed RNA polymerase, beta subunit
MG342      29.96         70           340           359        Mycoplasma-specific conserved hypothetical protein
MG343      25.05 *       82           172           240        Mycoplasma-specific hypothetical protein
MG344      27.84         85           200           286        probable esterase/lipase 3
MG345      27.26         67           195           288        isoleucyl-tRNA synthetase
MG346      28.92         89           265           338        rRNA methylase, trmH family
MG347      25.87 *       87           262           323        conserved hypothetical protein
MG348       35.2        122           215           284        Mycoplasma-specific hypothetical protein
MG349      28.38        108           217           242        Mycoplasma-specific hypothetical protein
MG350      25.51 *       76           236           341        Mycoplasma-specific hypothetical protein
MG350.1    27.53        143           231           283        Mycoplasma-specific hypothetical protein
MG351      28.44        154           233           312        inorganic pyrophosphatase
MG352      29.32        191           338           418        conserved hypothetical protein
MG353      32.42        144           420           464 *      Mycoplasma-specific hypothetical protein
MG354      26.76         98           375           457 *      Mycoplasma-specific conserved hypothetical protein
MG355      31.14         79           173           261        ATP-dependent Clp protease, ATPase subunit B
MG356       27.5        100           266           359        Mycoplasma-specific conserved hypothetical protein
MG357       29.6         89           252           363        acetate kinase
MG358      27.56        105           272           336        Holliday junction DNA helicase subunit A
MG359      29.21         86           239           315        Holliday junction DNA helicase subunit B
MG360      25.47 *      180           326           408        conserved hypothetical protein (probable DNA repair
                                                               protein Rev1)
MG361      30.25        151           291           343        50S ribosomal protein L10
MG362      34.97        281 ***       355           429        50S ribosomal protein L7/L12
MG363      39.77 **     396 *****     584 ***       536 **     50S ribosomal protein L32
MG363.1    24.62 *      293 ***       485 **        559 **     30S ribosomal protein S20
MG364      29.46        110           225           313        conserved hypothetical protein
MG365      27.97        100           285           378        methionyl-tRNA formyltransferase
MG366      22.99 **     129           271           365        Mycoplasma-specific hypothetical protein
MG367      27.74        161           252           300        ribonuclease III protein
MG368      29.98        154           241           342        fatty acid and phospholipid synthesis protein
MG369      30.28         96           265           334        conserved hypothetical protein
MG370      26.73         72           253           337        conserved hypothetical protein (possible
                                                               pseudouridylate synthase)
MG371      31.38         96           277           339        conserved hypothetical protein
MG372      27.19        132           240           335        conserved hypothetical protein
MG373      27.76        133           282           348        conserved hypothetical protein
MG374       26.4        129           282           358        Mycoplasma-specific hypothetical protein
MG375      28.43         99           258           311        threonyl-tRNA synthetase
MG376      30.13        226 **        402           468 *      Mycoplasma-specific hypothetical protein (basic)
MG377      27.98        143           281           371        conserved hypothetical protein
MG378      26.94        115           218           324        arginyl-tRNA synthetase
MG379      29.41         82           203           304        glucose inhibited division protein A
MG380      24.13 **     111           344           426        glucose inhibited division protein B
MG381      23.55 **     167           351           442        Mycoplasma-specific hypothetical protein
MG382      29.73        104           245           325        uridine kinase
MG383      29.97        128           282           365        NH(3)-dependent NAD+ synthetase
MG384      30.33        112           253           348        probable OBG-related Spo0B-associated GTP-binding
                                                               protein
MG384.1    23.94 **     185           312           357        conserved hypothetical protein
MG385      27.68        171           295           327        probable glycerophosphodiester phosphodiesterase
MG386       32.3        196 *         232           330        protein P200, cytadherence accessory protein
MG387      25.17 *      105           238           338        GTP-binding protein
MG388      30.36        172           375           348        conserved hypothetical protein
MG389      25.72 *      181           392           451 *      Mycoplasma-specific hypothetical protein
MG390      28.08         90           166           268        probable ABC transport protein; MSD-NBD fusion
                                                               protein
MG391         34        110           236           340        cytosol aminopeptidase (leucyl aminopeptidase)
                                                               (leucine aminopeptidase) (peptidase S)
MG392      33.76         98           197           275        60 kD chaperonin protein (heat shock protein)
MG393      34.85        115           399           394        10 kD chaperonin protein (heat shock protein)
MG394      34.07         80           194           257        serine hydroxymethyl transferase
MG395      30.53         62           175           262        Mycoplasma-specific conserved hypothetical protein
MG396      33.33         90           331           349        galactoside acetyltransferase (galactose-6-phosphate
                                                               isomerase)
MG397       25.5 *      132           201           285        conserved hypothetical protein
MG398      29.07        205 *         381           458 *      ATP synthase F1, subunit epsilon
MG399      34.64         69           237           331        ATP synthase F1, subunit beta
MG400      29.15         82           255           289        ATP synthase F1, subunit gamma
MG401      32.37         56           198           294        ATP synthase F1, subunit alpha
MG402      25.57 *      159           294           361        ATP synthase F1, subunit delta
MG403      28.85        236 **        228           304        ATP synthase F1, subunit b
MG404      34.64        192           326           427        ATP synthase F0, subunit C (lipid-binding protein)
MG405      29.91        168           320           368        ATP synthase F0, subunit A (protein 6)
MG406      26.55        220 **        454 *         524 **     hypothetical protein (basic)
MG407      32.68        124           227           320        enolase
MG408      28.03         98           327           428        peptide methionine sulfoxide reductase
MG409      26.22        160           266           345        probable phosphate transport system regulatory
                                                               protein PhoOU
MG410      29.18        154           238           303        phosphate ABC transporter, ATP-binding protein
MG411      27.68         83           226           336        phosphate ABC transporter, permease protein
MG412      28.56         93           242           286        Mycoplasma-specific conserved hypothetical protein
                                                               (possible phosphate-binding protein)
MG413      24.63 *       96           188           301        conserved hypothetical protein
MG414      25.71 *      112           182           294        conserved hypothetical protein
MG415      20.96 **     187           272           371        Mycoplasma-specific conserved hypothetical protein
MG417      32.32        180           405           436        30S ribosomal protein S9
MG418      30.59        109           282           375        50S ribosomal protein L13
MG419      25.32 *      160           243           314        Mycoplasma-specific hypothetical protein
MG420       29.1         90           292           333        DNA polymerase III gamma and tau subunits
MG421       30.7         73           208           291        excinuclease ABC subunit A
MG422      24.03 **     123           160           253        Mycoplasma-specific conserved hypothetical protein
MG423      29.65         86           182           276        conserved hypothetical protein (basic)
MG424      30.62        182           351           336        30S ribosomal protein S15
MG425      30.44         84           229           282        probable ATP-dependent RNA helicase
MG426      32.29        237 **        628 ***       680 ****   50S ribosomal protein L28
MG427       35.7        168           355           384        Mycoplasma-specific conserved hypothetical protein
MG428      27.88        252 **        309           372        Mycoplasma-specific conserved hypothetical protein
MG429      30.07         66           203           302        PEP protein phosphoryltransferase (PTS enzyme I)
MG430      31.03        100           245           327        phosphoglycerate mutase
MG431       30.6        121           300           388        triosephosphate isomerase
MG432      29.15         87           277           328        conserved hypothetical protein (basic)
MG433      27.29         88           261           333        translation elongation factor Ts
MG434      30.51        198 *         383           448 *      uridylate kinase
MG435      27.87        143           285           372        ribosome recycling factor (ribosome releasing
                                                               factor)
MG436      29.38        233 **        481 **        485 *      hypothetical protein (basic)
MG437      30.05        146           234           330        probable CDP-diglyceride synthetase
MG438      30.46         79           225           305        type I restriction enzyme S protein
MG439      29.04        137           333           378        Mycoplasma-specific conserved hypothetical
                                                               lipoprotein (basic) (M. genitalium predicted coding
                                                               region MG439)
MG440      29.59        128           290           373        Mycoplasma-specific conserved hypothetical
                                                               lipoprotein (M. genitalium predicted coding region
                                                               MG440)
MG441       22.3 **     237 **        372           450 *      Mycoplasma-specific conserved hypothetical protein
                                                               (basic) (M. genitalium predicted coding region
                                                               MG441)
MG442      27.53        141           242           334        conserved hypothetical protein (basic)(GTP-binding
                                                               protein)
MG443      28.61         98           227           291        conserved hypothetical protein (basic)
MG444      32.49        118           411           464 *      50S ribosomal protein L19
MG445      28.43         45           339           400        tRNA (guanine-N1)-methyltransferase
MG446      34.08        201 *         511 **        540 **     30S ribosomal protein S16
MG447      26.81        118           235           322        Mycoplasma-specific conserved hypothetical protein
                                                               (basic)
MG448      32.89        149           351           375        conserved hypothetical protein (peptide methionine
                                                               sulfoxide reductase homolog)
MG449      30.32        142           339           429        conserved hypothetical protein (basic)
MG450      31.22        149           289           323        Mycoplasma-specific conserved hypothetical protein
MG451      39.34 **      73           238           286        elongation factor TU
MG452      26.56        156           344           424        Mycoplasma-specific conserved hypothetical protein
MG453      31.05         87           257           321        UTP--glucose-1-phosphate uridyltransferase (UDPGP)
MG454      29.25         97           327           414        conserved hypothetical protein
MG455      26.78        103           256           360        tyrosyl-tRNA synthetase
MG456      27.54        124           241           334        Mycoplasma-specific hypothetical protein
MG457      34.62         58           191           264        FTSH cell division protein
MG458      30.86        139           364           413        hypoxanthine-guanine phosphoribosyltransferase
MG459      29.98        121           359           386        conserved hypothetical protein
MG460      33.55        128           302           382        lactate/malate dehydrogenase
MG461      27.84         92           194           277        conserved hypothetical protein
MG462      30.72         77           190           246        glutamyl-tRNA synthetase
MG463      28.19        123           321           371        dimethyladenosine transferase
MG464      31.69        104           248           258        conserved hypothetical protein (probable membrane
                                                               protein)
MG465      31.51        225 **        334           312        probable ribonuclease P component
MG466      41.67 **     238 **        613 ***       634 ***    50S ribosomal protein L34
MG467      30.76        130           264           281        ATP-binding protein, probable ABC transporter,
                                                               probable maturation protein
MG468      30.92         52           131           226        conserved hypothetical protein (possible 5'-3'
                                                               exonuclease)
MG468.1    29.69        103           219           293        ABC transporter, ATP binding protein
MG469      27.54        127           247           328        chromosome replication initiator protein
MG470      29.99        110           405           470 *      SOJ protein (SpoOJ regulator)


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